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Characterization of bendless and interacting partners in Drosophila central synapse formation
Neurons signaling pathways websites molecular nervous system diseases diseases central synapses fiber system the neural network
2014/12/11
Synapses are the functional units of neuronal circuits and the sites of integration for multiple signaling pathways. Understanding the molecular basis of synaptic function is critical to understanding...
Approximate invariance of metabolic energy per synapse during development in mammalian brains
Synaptogenesis brain metabolism model synaptic density firing rate
2012/5/2
During mammalian development the cerebral metabolic rate correlates qualitatively with synaptogenesis, and both often exhibit bimodal temporal profiles. Despite these non-monotonic dependencies, it is...
HIV-1 NEF: THERAPEUTIC STRATEGIES AND VIROLOGICAL SYNAPSE-MEDIATED INFECTION
THERAPEUTIC STRATEGIES VIROLOGICAL SYNAPSE-MEDIAT
2015/5/21
HIV-1 infection is one of the greatest public health concerns today. The current HIV/AIDS therapy is effective in halting virus multiplication and has improved the outlook of AIDS; however, high cost,...
The squid giant synapse, which permits intracellular electrical measurements in a single, excitatory synapse, was exposed to helium pressures up to 204 atm. By stimulating presynaptically and recordin...
T cell signaling: Protein kinase Cθ, the immunological synapse and characterization of SLAT, a novel T helper 2-specific adapter protein
immune synapse protein kinase Cθ SLAT T cell receptor CD28 Th2
2010/11/24
Triggering of the antigen-specific T cell receptor (TCR) can lead to various functional outcomes, such as activation and proliferation, anergy or cell death. This differential signaling is mainly dete...