搜索结果: 1-11 共查到“知识库 Systems biology”相关记录11条 . 查询时间(0.132 秒)
When one model is not enough:Combining epistemic tools in systems biology
modeling reverse engineering network motifs Rheinberger engineering analogies historical epistemology
2016/6/13
In recent years, the philosophical focus of the modeling literature has shifted from descriptions of general properties of models to an interest in different model functions. It has been argued that t...
Tracing organizing principles:Learning from the history of systems biology
systems biology organizing principles general systems theory design principles mathematical modeling
2016/6/13
With the emergence of systems biology the notion of organizing principles is being highlighted as a key research aim. Researchers attempt to ‘reverse engineer’ the functional organization of biologica...
Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation
Systems biology integration mechanistic explanation mathematical models mechanisms
2016/6/12
The paper discusses how systems biology is working toward complex accounts that integrate explanation in terms of mechanisms and explanation by mathematical models—which some philosophers have viewed ...
ONTOLOGY-DRIVEN AND NETWORK–ENABLED SYSTEMS BIOLOGY CASE STUDIES
bioinformatics Integration of genomics
2015/5/27
With the progress in high-throughput technologies and bioinformatics in recent years, it is possible to determine to what extent genetic or environmental manipulation of a biological system affects th...
Towards a Comprehensive Human Pathway Database For Systems Biology Applications
Systems Biology Applications Human Pathway Database
2015/5/26
A biological pathway is a series of reactions and molecular interactions. Pathway information provides a blueprint for biomedical researchers to devise new treatment and diagnostic solutions for human...
Factored expectation propagation for input-output FHMM models in systems biology
input output factored hidden Markov models approximate inference variational inference expectation propagation systems biology microarray data
2013/6/14
We consider the problem of joint modelling of metabolic signals and gene expression in systems biology applications. We propose an approach based on input-output factorial hidden Markov models and pro...
An integrative systems biology approach for analyzing liver hypermetabolism
hypermetabolism gene expression regulation
2009/12/24
Severe injury and other disease conditions (cancer, diabetes) lead to a hypermetabolic
state featuring increased turnover of proteins, fatty acids and carbohydrates. Prolonged
hypermetabolism is a...
Nano-Biodevice for Genomic Medicine and Systems Biology
nanotechnology nano-biodevice genomics proteomics systems biology
2007/12/13
Nano-Biodevice for Genomic Medicine and Systems Biology。
Review of "Stochastic Modelling for Systems Biology" by Darren Wilkinson
Stochastic Modelling Systems Biology Darren Wilkinson
2010/2/26
"Stochastic Modelling for Systems Biology" by Darren Wilkinson introduces the peculiarities of stochastic modelling in biology. This book is particularly suited to as a textbook or for self-study, and...
Systems Biology-Toward System-level Understanding of Biological Systems
Systems Biology-Toward System-level
2014/3/31
System Design: the strategies to modify and construct biological systems having desired properties can be devised based on definite design principles and simulations, instead of blind trial-and-error.
Systems Biology: An Information-Theoretic-Based Thermo-Statistical Approach
Systems Biology biological science nonequilibrium statistical mechanics
2010/10/19
Systems Biology (system-level understanding in biological science), from the physical-chemical point of view, is involved with irreversible thermodynamics and nonlinear kinetic theory of open systems ...