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关节处软骨细胞由于缺乏血供和神经支配,自我修复能力有限。这使得临床上关节软骨的再生是一个巨大挑战。细胞疗法被认为是修复受损关节软骨的重要方法。骨髓间充质干细胞由于其多向分化潜能和免疫调节能力,已成为关节软骨修复的潜在治疗手段。临床实验证明这类间充质干细胞对软骨类疾病具有一定的改善。但是这些干细胞往往形成纤维软骨或者在修复过程中展示出副作用,且在体外扩培的过程中容易衰老,其分化潜能会因为患者衰老而减...
A newly identified stem cell regulator enables lifelong sperm production(图)
干细胞调节器 干细胞更新因子 细胞工程
2023/7/10
印第安纳大学医学院的研究人员成功地将中枢神经系统中的一种胶质细胞重新编程为新的神经元,以促进脊髓损伤后的恢复——揭示了利用这种细胞进行再生医学的尚未开发的潜力。
研究小组于 3 月 5 日在《Cell Stem Cell》杂志上发表了他们的研究结果。这是科学家首次报道在脊髓损伤后将 NG2 胶质细胞(中枢神经系统中的一种支持细胞)改造成功能性神经元。
Super Resolution Imaging Helps Determine a Stem Cell’s Future
Super Resolution Imaging Stem Cell Future
2017/3/14
Scientists at Rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible.Understanding a stem cell’s fate – the type...
Discovery of new stem cell pathway indicates route to much higher yields in maize,staple crops
new stem cell pathway much higher yields maize staple crops
2016/5/19
Biologists at Cold Spring Harbor Laboratory (CSHL) have made an important discovery that helps explain how plants regulate the proliferation of their stem cells. The discovery has near-term implicatio...
TSRI and JCVI Scientists Find Popular Stem Cell Techniques Safe
TSRI JCVI Scientists Stem Cell Techniques
2016/3/2
A new study led by scientists at The Scripps Research Institute (TSRI) and the J. Craig Venter Institute (JCVI) shows that the act of creating pluripotent stem cells for clinical use is unlikely to pa...
Stem cell treatment lessens impairments caused by dementia with Lewy bodies
Stem cell treatment lessens impairments dementia with Lewy bodies
2015/11/12
Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of Califor...
The University of Queensland stem cell researcher leads high school activity for National Science Week
stem cell bioinformatics
2014/7/15
A University of Queensland stem cell researcher will lead a discussion of Year 10 students from around Australia, covering genomics, bioinformatics and stem cell research on Thursday, August 16 for Na...
Development of stem cell research for treating human cells damaged through injury, disease or ageing has taken a step forward in Queensland.
The University of Queensland researchers make breakthrough in stem cell research(图)
stem cell research
2014/7/17
University of Queensland scientists have developed a world-first method for producing adult stem cells that will substantially impact patients who have a range of serious diseases.
For the past two decades, scientists have been trying to fulfill the promise that stem-cell therapy holds for treating diseases such Parkinson’s, Alzheimer’s and many others. Their ultimate goal is to...
Visionary stem cell technique offers new potential to treat blindness
Visionary stem cell technique new potential blindness
2010/10/25
Scientists funded by the Medical Research Council (MRC) are pioneering a stem cell treatment to replace diseased parts of the retina, which could lead to a future treatment for retinal diseases that a...
Ogle earns CAREER award for contributions to stem cell analysis
Ogle CAREER award stem cell analysis
2009/12/21
While a benefit of stem cells lies in their potential to develop into many cell types, that tendency to differentiate also frustrates researchers trying to study stem cells without disturbing them. “M...
Taking aim at aggressive cancer cells--Researchers use novel stem-cell method to discover chemical with potency against breast tumors in mice
cancer cells stem-cell method breast tumors mice
2009/8/18
A team of researchers led by the Whitehead and Broad Institutes has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed n...