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Adjusting for Treatment Effects in Studies of Quantitative Traits
Quantitative traits Imputation QTL mapping Single-marker analysis Mixed models Kruskal-Wallis test
2013/6/14
A population-based study of a quantitative trait, e.g. Blood Pressure(BP) may be seriously compromised when the trait is subject to the effects of a treatment. Without appropriate corrections this can...
Efficient Algorithms for Multivariate Linear Mixed Models in Genome-wide Association Studies
Efficient Algorithms Multivariate Linear Mixed Models Genome-wide Association Studies
2013/6/17
Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, existing...