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Thymoquinone Suppresses Cellular Proliferation, Inhibits VEGF Production and Obstructs Tumor Progression and Invasion in the Rat Model of DMH-Induced Colon Carcinogenesis
Thymoquinone PCNA-LI VEGF Serum Levels
2013/2/19
A myriad of medicinal effects has been attributed to Thymoquinone (TQ), the major biological-active component of Nigella sativa. TQ has been shown to exhibit potent anti-tumor activities. The present ...
Administration of anti-glucagon-like peptide-2 serum suppresses epithelial cell proliferation of the distal small intestine in weanling rats
weanling rats cell proliferation
2009/12/16
We investigated the effects of endogenous glucagon-like peptide-2 (GLP-2) on the development of intestinal mucosa in weanling rats. Three-week-old male weanling Sprague-Dawley rats were administered e...
Blockers of K+/Cl- transporter/channels diminish proliferation of osteoblastic cells
K+/Cl- transporter/channels osteoblastic cells
2009/5/8
In the preset report, we studied if blockers of the K+/Cl- cotransporter, and Cl- and K+ channels modify the proliferation of MC3T3-E1 osteoblastic cells. A blocker of the K+/Cl- cotransporter, DIOA...
Different Effects of Regulatory Genes (tat, nef) of Human Immunodeficiency Virus Type 1 (HIV-1) on the Proliferation and Differentiation of Mouse Embryonic Stem Cells in vitro
embryonic stem cells regulatory genes of human immunodeficiency virus transfection embryoid bodies
2009/4/29
To examine the effects of the tat and nef regulatory genes of human immunodeficiency virus (HIV-1) on cell differentiation we used the mouse embryonic stem cells (ESC) as a model. Proliferation, embry...
Sildenafil Inhibits the Proliferation of Cultured Human Endothelial Cells
atherosclerosis basic fibroblast growth factor endothelial proliferation plaque angiogenesis
2009/4/20
The proliferation of endothelial cells plays a crucial role in the development of intraplaque angiogenesis (IPA). IPA is a major source of intraplaque hemorrhage and therefore contributes to the desta...
Effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and proliferation of HO-8910 cell line of ovarian cancer
3`-azido-3`-deoxythymidine (AZT) reverse transcriptase inhibitor telomerase proliferation ovarian carcinoma cell
2009/4/20
Objective: To study the effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and the proliferation of ovarian cancer cells in vitro. Methods: Telomerase activity was detected by enzyme ...
Hepatocyte growth factor regulates the proliferation and differentiation of cartilage in developing forelimb of mouse embryos in vitro
Hepatocyte growth factor proliferation cartilage mouse embryos
2009/3/3
We examined the role of hepatocyte growth factor (HGF) in the chondrogenesis and endochondral ossification in the forelimbs of mouse embryos by use of immunohistochemistry and organ culture system. ...
Effect of a diode laser on cell proliferation, alkaline phosphatase activity, and osteopontin mRNA expression in proliferating and in differentiating osteoblastic cells
cell proliferation alkaline phosphatase activity osteopontin mRNA expression
2009/3/3
Different types of osteoblast behavior result from external stimulation in the early and in the late stages of cell differentiation. The purpose of this study was to investigate the influence of a d...
Normalization of high-flow or removal of flow cannot stop high-flow induced endothelial proliferation
Normalization high-flow endothelial proliferation
2009/3/2
Endothelial cells (ECs) are activated in response to high-flow. Our previous studies using arteriovenous fistula (AVF) model have demonstrated that high-flow in blood vessels induces an early and ra...
Continuous carbachol infusion promotes peripheral cell proliferation and mimics vagus hyperactivity in a rat model of hypothalamic obesity
Continuous carbachol infusion promotes peripheral cell proliferation mimics vagus hyperactivity hypothalamic obesity
2009/3/2
Lesions of the ventromedial hypothalamus (VMH) result in obesity and enhanced cellular proliferation in various organs, including the pancreas, gastrointestinal tract, and liver. Previous studies ha...
Effects of estrogens on proliferation and differentiation of neural stem/progenitor cells
estrogens proliferation neural stem/progenitor cells
2009/3/2
We investigated the effect of the female hormone 17β-estradiol (E2) and the hormone mimic bisphenol A (BPA) on the proliferation and differentiation of rat neural stem/progenitors cells (NS/PCs) cul...
Period is involved in the proliferation of human pancreatic MIA-PaCa2 cancer cells by TNF-α
proliferation human pancreatic MIA-PaCa2 cancer cells TNF-α
2009/3/2
Recent studies have found alterations to clock genes in several forms of cancer. Period (Per) gene plays an important role in the circadian system, the cell cycle, the induction of apoptosis, and DN...