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Aspirin targets key protein in neurodegenerative diseases
Aspirin protein neurodegenerative diseases
2015/12/7
A new study finds that a component of aspirin binds to an enzyme called GAPDH, which is believed to play a major role in neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s...
Flavin-Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells
Rat Microvascular Endothelial Cells Flavin-Containing Monooxygenase (FMO)
2013/2/19
The aim of this study was to examine whether flavin-containing monooxygenase (FMO) protein was expressed in cultured rat brain microvascular endothelial cells (BMECs), which constitute the blood-brain...
Effect of Iron-Mediated Oxidative Stress on Insulin Resistance Through the Forkhead Box-Containing Protein O Subfamily-1 (FOXO-1) Pathway in Chronic Hepatitis C
Chronic Hepatitis C Gluconeogenesis Insulin Resistance Iron Metabolism Oxidative Stress
2013/1/29
Aims: Chronic hepatitis C virus (HCV) infection is often associated with glucose metabolic disorders and iron overload. It has recently been shown that reactive oxygen species (ROS) increase gluconeog...
Influence of Varying Crude Protein Levels and Balanced Amino Acids on the Performance and Haematological Characteristics of Laying Hens at the Second Phase of Production
Varying Crude Protein Balanced Amino Acids Laying Hen Second Phase
2013/1/29
Varying levels of dietary crude proteins and balanced amino acids were fed to layers for a period of eight weeks starting from the twenty-sixth week of age of birds and six weeks into egg production. ...
Influence of bone morphogenetic protein on articular cartilage regeneration following periosteal grafting
Bone Morphogenetic Protein (BMP) Articular Cartilage Regeneration Periosteal Grafting
2013/1/28
Background: Autologous periosteal grafting is used as treatment for articular cartilage defect. Objective: To study the effect of bone morphogenetic protein (BMP) on articular cartilage regeneration f...
The Distribution of the Stress Protein HSP70 in the Cerebellum of Patients with Schizophrenia
Biological Marker Post Mortem Heat Shock Protein Cerebellum Schizophrenia
2013/1/30
Data accumulated from neuro-imaging, clinical and morphological studies suggest that the cerebellum is involved in cognitive functions and thus may be important in the etiopathogenesis of schizophreni...
Comparison of protein concentrations in serum versus plasma from Alzheimer’s patients
Alzheimer’s Disease Serum Proteins Plasma Proteins
2013/1/28
Background: There is great interest in developing blood-based biomarkers for Alzheimer’s disease (AD); however, there is no consensus as to what blood fraction is most appropriate for analyzing partic...
Description of a Putative Oligosaccharyl:S-Layer Protein Transferase from the Tyrosine O-Glycosylation System of Paenibacillus alvei CCM 2051T
Bacterial Glycosylation S-Layer Oligosaccharyl Transferase
2013/1/29
Surface (S)-layer proteins are model systems for studying protein glycosylation in bacteria and simultaneously hold promises for the design of novel, glyco-functionalized modules for nanobiotechnology...
Localization of the VP2 Protein of Canine Parvovirus Type 2 on the Baculovirus Envelop and Its Immunogenicity in a Mouse Model
Canine Parvovirus Type 2 VP2 Protein Baculovirus gp64 TM and CTD Subunit Vaccine
2013/2/19
In this study, the full-length VP2 gene of canine parvovirus type 2 (CPV-2) was cloned into the pBacSC vector which possesses baculovirus transmembrane domain (gp64 TM) gene, baculovirus cytoplasmic d...
Immunoexpression of Cathepsin D and S100A4 Protein and Their Molecular Subtyptes in Canine Mammary Carcinomas
Cathepsin Mammary Tumors Metastasis-Associated Proteins Molecular Subtypes S100 Protein
2013/2/19
Cathepsin D (CD), a lysosomal protease, and S100A4 protein, a calcium binding motif, are considered to be involved in metastasis in various human cancers. No data regarding such proteins are available...
Calcium Integrin Binding Protein Associates with Integrins αVβ3 and αIIbβ3 Independent of β3 Activation Motifs
Leukocyte lntegrin Cytoskeleton Hematopoietic Activation Signaling
2013/1/29
The Calcium Integrin Binding protein (CIB) has been identified as interacting specifically with the cytoplasmic tail of the integrin αIIb domain to induce receptor activation and integrin αIIbβ3 media...
Correlation of Serum C-Reactive Protein with Disease Severity in Tuberculosis Patients
Acid Fast Bacilli Serum C-Reactive Protein Tuberculosis Directly Observed Therapy Short-Course
2013/1/31
Purpose: To study the factors influencing sputum smear conversion including Serum C-Reactive Protein (CRP) and its correlation with disease severity in tuberculosis patients. Method: Levels of Serum-C...
A Deterministic Global Optimization Approach for the Protein Folding Problem
A Deterministic Global Optimization Approach the Protein Folding Problem
2009/12/24
A Deterministic Global Optimization Approach for the Protein Folding Problem.
Automated Interpretation of Protein Subcellular Location Patterns: Implications for Early Cancer Detection and Assessment
Protein Subcellular Location Patterns Early Cancer Detection
2009/12/23
Automated Interpretation of Protein Subcellular Location Patterns: Implications for Early Cancer Detection and Assessment.
AUTOMATED DETERMINATION OF PROTEIN SUBCELLULAR LOCATIONS FROM 3D FLUORESCENCE MICROSCOPE IMAGES
3D FLUORESCENCE MICROSCOPE IMAGES AUTOMATED
2009/12/23
Knowing the subcellular location of a protein is critical to
a full understanding of its function, and automated,
objective methods for assigning locations are needed as
part of the characterizatio...