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Our laboratory has previously identified the clock gene D-box Binding Protein (DBP) as a candidate gene for bipolar disorder and alcoholism using a Convergent Functional Genomics (CFG) approach. In su...
A critical goal of translational research is to convert basic science to clinically relevant actions related to disease prevention, diagnosis, and eventually enable physicians to identify and evaluate...
Transparent stereolithographic rapid prototyping (RP) technology has already demonstrated in literature to be a practical model construction tool for optical flow measurements such as digital particle...
The response of the vascular endothelium to wall shear stress plays a central role in the development and progression of atherosclerosis. Current studies have investigated endothelial response using i...
Image-based change quantitation has been recognized as a promising tool for accurate assessment of tumor's early response to chemoprevention in cancer research. For example, various changes on breast ...
Recent advances in neuroimaging techniques have provided precise spatial localization of brain activation applied in several neuroscience subareas. The development of functional magnetic resonance ima...
As a consequence of misspecification of the hemodynamic response and noise variance models, tests on general linear model coe cients are not valid. Robust estimation of the variance of the general lin...
Diffusion tensor imaging (DTI) is considered to be a promising tool for revealing the anatomical basis of functional networks. In this study, we investigate the potential of DTI to provide the anatomi...
The KF/SQI-fusion method described in this article was shown to provide an accurate estimate of blood pressure and HR derived from the ABP waveform even in the presence of high levels of persistent no...
The effect of magnetic stimulation for the treatment of urinary incontinence has been explained as a re-activation of lost functions of the pelvic floor muscles. A model study was used to investigate ...
An optical method recently proposed for non-invasive in vivo blood glucose concentration (BGL) measurement, named “Pulse Glucometry”, was combined and compared with four multivariate analyses for cons...
We established models of cancer-related anemia in mice from subcutaneous inoculation of two IL-6-producing cancer cell lines, human lung cancer cell line LC-06-JCK and murine colon26 clone 5 colon c...
All models showed an excellent goodness-of-fit (R2 always above 0.92). There were significant differences between the models in the parameters derived from the inspiratory limb, but not in those deriv...
The reference model (Model 1), as expected, performed best in localizing the sources in the motor cortex area. The Model 3 performed the worst. The mean source localization errors (MLEs) of the Model ...

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