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Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 Cells
caspases calcium signal apoptosis mitochondria H2O2 HL-60 cells
2009/10/26
The present study is aimed to determine the role of calcium signaling evoked by the oxygen radical, hydrogen peroxide (H2O2) and the specific inhibitor of calcium reuptake thapsigargin on apoptosis in...
Construction of HeLa cell lines overexpressing metallothioneins-1 and -2 and their cytoprotective effects against oxidative damage induced by hydrogen peroxide
cell viability copper cytoprotective effect HeLa cell metallothionein
2009/4/1
It has been suggested that metallothioneins (MTs) play a role to protect cells from toxic effects of oxidative stress and heavy metals. On the other hand, the ability of Cu-containing MT to protect ce...