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New model reveals possibility of pumping antibiotics into bacteria（图）
New model possibility pumping antibiotics bacteria
2017/11/23
Researchers in the University of Wisconsin–Madison Department of Biochemistry have discovered that a cellular pump known to move drugs like antibiotics out of E. coli bacteria has the potential to bri...
Laboratory Exercises to Teach Clinically Relevant Chemistry of Antibiotics
drug interactions ß -lactam antibiotics medicinal chemistry
2018/7/3
Objectives. To design, implement, and evaluate student performance on clinically relevant chemical and spectral laboratory exercises on antibiotics.
Design. In the first of 2 exercises, second-year p...
A Multicenter Study on the Prophylactic Application of Antibiotics in Aseptic Operations
Anti-Bacterial Agents Aseptic Analysis
2015/9/29
Perioperative prophylactic use of antibiotics aims to prevent bacterial invasion of the wound from entering blood circulation and secondary infection, but antibiotics are mostly not in need unless con...
提高产抗生素链霉菌紫外诱变正变率的研究Studies of Increasing the Forward-mutation Rate ofUV Irradiated Streptomyces sp. AP 19―1, an Antibiotics Producing Strain
紫外诱变 链霉菌 正突变体 RAPD
2008/1/8
摘要
将UV诱变了的产抗生素链霉菌（Streptomyces sp.）AP 19-1菌株之孢子，置于适宜的生长温度27℃与接近抑制生长的胁迫温度33℃下培养，结果表明：在33℃下生长获得的子代菌株中，产抗生素水平超过其出发菌株的正向突变体所占的比例，明显比在27℃下培养的高。27℃下培养，正向突变体占总子代菌株数的25.8%，而在33℃下培养则为58.1%。用17种随机引物对出发菌株与UV诱变...
Antibiotics: Mechanisms of Action and Acquisition of Resistance—When Magic Bullets Lose Their Magic
Antibiotics: Mechanisms Action Acquisition Resistance Magic Bullets Lose Magic
2016/3/10
This lecture discusses mechanisms of antibiotic activity as an introduction to a closer look at the diverse mechanisms of innate and acquired, transferable/nontransferable drug resistance. The emergen...