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Tumour cells secrete small membrane vesicles (30-100nm) termed exosomes, that are derived from late endosomal compartments of cells. Exosomes are increasingly being recognised for their role in interc...
BME Researchers Identify Proteins That May Provide Lung Cancer Drug Targets
BME Researchers Proteins Lung Cancer Drug Targets
2009/12/17
Researchers from the Biomedical Engineering Department and the Boston University School of Medicine have identified a number of proteins which, when activated, allow researchers to distinguish between...
Individual CDR3 Regions as Targets for Detection of Clonal Cells in Acute Lymphocytic Leukemia
Minimal residual disease Acute lymphocytic leukemia CDR3
2009/6/26
Immunoglobulin heavy chain rearrangements provide a specific identity of complementarity determining region 3 (CDR3) DNA sequences. For this reason, CDR3 regions may be used in the diagnosis of malign...