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探讨乙酰肝素酶（Heparanase）对结肠癌细胞生物学功能的影响。方法 采用荧光定量PCR检测人结肠癌细胞株SW620、SW480、LoVo和CACO2中Heparanase的表达水平；设计并合成3条Heparanase特异性的小分子干扰RNA（siRNA1、siRNA2、siRNA3），用于转染4株结肠癌细胞中Heparanase表达水平最高者；荧光定量PCR和Western blottin...
Heparanase Expression Correlates with Angiogenesis and Lymphangiogenesis in Human Lung Cancer
Lung Neoplasms Heparanase Vascular Endothelial Growth Factor-C Lymphatic Metastasis
2013/12/10
Background and objective Heparanase has been thought to be a good molecular marker of tumor, and the heparanase expression level correlated closely with tumor metastasis. In this study, we investigate...