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Round spermatids show normal testis-specific H1t but reduced cAMP-responsive element modulator and transition protein 1 expression in men with round-spermatid maturation arrest
ene expression human testis spermatogenic impairme
2009/2/18
During spermiogenesis, histones are replaced by transition proteins, which in turn are replaced by protamines. The TNP1 gene-encoding TP1 (transition protein 1) protein contains a cAMP-responsive el...
Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors
Epididymis efferent duct ligation F4/80 Mac-i
2009/2/18
Factors controlling the appearance in the epididymis of basal cells and their expression of macrophage antigens were examined by ligating the efferent ducts to prevent the entry of spermatozoa in ad...
Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors
Epididymis efferent duct ligation F4/80 Mac-i
2009/2/18
Factors controlling the appearance in the epididymis of basal cells and their expression of macrophage antigens were examined by ligating the efferent ducts to prevent the entry of spermatozoa in ad...
Molecular cloning and developmental expression of the major fibrous sheath protein（FS 75）of rat sperm
Molecular cloning developmental expression major fibrous sheath protein（FS 75） rat sperm
2009/2/18
The fibrous sheath (FS) is a cytoskeletal structure that encases the axoneme in the principal piece of the spermatozoon tail. In the rat, it is composed of several proteins, of which a 75-kDa polype...
Contrin, the human homologue of a germ-cell Y-box-binding protein：cloning, expression, and chromosomal localization
human homologue germ-cell Y-box-binding protein chromosomal localization
2009/2/18
Inactivation of germ-cell-specific molecules essential for the production of functional spermatozoa could lead to attractive new means for male contraception. The mouse protein MSY2 is the mammali...
Expression of cyclin-dependent kinase 5 and associated cyclins in Leydig and Sertoli cells of the testis
cyclin-dependent kinase 5 associated cyclins Leydig and Sertoli cells
2009/2/18
In this study, we examined the expression and subcellular localization of cyclin-dependent kinase 5 (Cdk5), cyclin D1, and cyclin E in Leydig and Sertoli cell lines that were cultured with 7.5, 1....
Selective expression of a glutathione S-transferase subclass during spermatogenesis
High-performance liquid chromatography development
2009/2/18
Levels of the hGSTM3 glutathione S-transferase (GST) subunit in testis of the human fetus and infant were found to be only a small fraction of those in adults. To understand these observations and...
The effects of aging on the expression of glutathione S-transferases in the testis and epididymis of the Brown Norway rat
glutathione S-transferases epididymis Brown Norway rat
2009/2/17
Glutathione S-transferases (GSTs), a family of isoenzymes, catalyze the conjugation of glutathione to a variety of electrophiles, and protect cellular constituents from electrophilic and oxidative...
Expression of 140-kDa neural cell adhesion molecule in developing testes in vivo and in long-term Sertoli cell-gonocyte cocultures
Testicular development cell adhesion NCAM immunostaining
2009/2/17
The basis for cell-cell adhesion in the seminiferous epithelium of the developing testis is doubtless critical in supporting events that are essential for the onset and maintenance of normal sperm...
Seminal vesicles are novel sites of luteinizing hormone/human chorionic gonadotropin-receptor gene expression
LH/hCG receptors male accessory organs gonadotropins
2009/2/17
The hypothesis that rat seminal vesicles may contain luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptors was tested by means of a number of different techniques. Northern blotting ...
Oxidative stress differentially regulates the expression of gamma-glutamyl transpeptidase mRNAs in the initial segment of the rat epididymis
gamma-glutamyl transpeptidase mRNAs initial segment rat epididymis
2009/2/17
Reactive oxygen species (ROS) have a powerful cytotoxic effect on spermatozoa and have been implicated in spermatozoal dysfunction and male infertility. gamma-Glutamyl transpeptidase (GGT) is esse...
Estrogen receptor（alpha and beta）expression in the excurrent ducts of the adult male rat reproductive tract
Efferent ductules immunohistochemistry
2009/2/17
The understanding of estrogen's function in the male reproductive tract is limited, and estrogen receptor (ER) localization in the reproductive tract of the adult male rat has not been described. ...
Stability and transcriptional regulation of gamma-glutamyl transpeptidase mRNA expression in the initial segment of the rat epididymis
Stability transcriptional regulation gamma-glutamyl transpeptidase mRNA initial segment rat epididymis
2009/2/17
Gamma-glutamyl transpeptidase (GGT) is an enzyme believed to play a role in the protection of maturing spermatozoa in the epididymis. Our previous studies have shown that four GGT mRNAs (I-IV) trans...
Low density lipoprotein receptor-related protein-1 expression in the testis：regulated expression in Sertoli cells
protein-1 testis regulated expression Sertoli cells
2009/2/17
The low density lipoprotein receptor-related protein (LRP-1) is a multiligand receptor capable of mediating endocytosis of a wide array of ligands that relate to both lipoprotein metabolism and pr...
Expression of clusterin/sulfated glycoprotein-2 under conditions of heat stress in rat Sertoli cells and a mouse Sertoli cell line
SGP-2 testis HSP7O
2009/2/17
Clusterin is the major protein produced by rat Sertoli cells and is deposited onto sperm membranes; however, its function is unknown. In order to gain insight into the regulation of clusterin in Serto...