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Involvement of endothelial nitric oxide synthase in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbit
Hypercholesterolemia cavernous smooth muscle
2009/2/18
The present study was designed to evaluate whether functional impairment and/or protein expression of constitutive nitric oxide synthase (cNOS; endothelial NOS [eNOS] and neuronal NOS[nNOS]) was i...
Overexpression of Endothelial Nitric Oxide Synthase in Transgenic Mice Accelerates Testicular Germ Cell Apoptosis Induced by Experimental Cryptorchidism
Immunoblotting TUNEL spermatocytes spermatids spermatogonia
2008/12/23
Surgical induction of cryptorchidism in experimental animals causes testicular germ cell apoptosis and infertility. The mechanisms of germ cell apoptosis have been associated with oxidative stress o...
Glu298Asp Endothelial Nitric Oxide Synthase Polymorphism Is a Risk Factor for Erectile Dysfunction in the Mexican Mestizo Population
Angiotensin-converting enzyme endothelial dysfunction impotence
2008/12/22
Penile erection depends on the balanced action between antagonist vasoactive molecules such as nitric oxide (NO) and angiotensin. Endothelial nitric oxide synthase (eNOS) and angiotensin-convertin...
Noncholinergic penile erection in mice lacking the gene for endothelial nitric oxide synthase
Noncholinergic penile erection gene endothelial nitric oxide synthase
2008/12/1
With the current understanding that nitric oxide (NO) mediates penile erection, the endothelial isoform of NO synthase (eNOS) has been implicated in this function. We undertook this study applying t...