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The presence of motility inhibitors in seminal plasma and within spermatozoa from control and infertile men with poor sperm motility was investigated using demembranated reactivated human spermatozo...
Leydig cells, purified on two sequential Percoll gradients to purities of 89 +/- 1%, were used to study the binding of 17-beta-hydroxy-17 alpha-methyl-estra-4,9,11-triene-3-one(3H-R1881). The accumu...
Repeated semen specimens were examined from 24 men who had been vasectomized for periods of time ranging from two to 31 years. Five-micron filters were used to collect the spermatozoa in each spec...
In an attempt to elucidate the effect of estradiol on the rat prostate, four experiments were conducted. In experiment 1, rats were orchiectomized and were given subcutaneous implants of silastic ...
The c-met receptor is a p190MET tyrosine kinase proto-oncoprotein that through its binding to its ligand, designated hepatocyte growth factor (HGF), induces mitogenic, motogenic, and morphogenic act...
Interleukin-12 (IL-12) is a unique cytokine that recently has drawn considerable attention because of its immunomodulatory properties and its possible involvement in several normal physiological a...
Sperm from four mammalian species were analyzed by the sperm chromatin structure assay (SCSA) and the terminal deoxynucleotidyl transferase assay (TdTA) using flow cytometry. The SCSA quantitates the ...
Charles River CD rats (approximate weight, 208 g) were exposed to 1.0% 2,5-hexanedione (2,5-HD) in drinking water for 5 weeks. Rats were killed 27, 60, and 75 weeks after exposure to evaluate the re...
To investigate the role of the serotoninergic system in regulating pulsatile gonadotropin secretion in man, we tested the influences of a novel selective serotonin re-uptake inhibitor (fluoxetine HC...
Some sexual responses in the male rat, specifically penile erection, are controlled by neural circuits in the brain and spine that are stimulated by the binding of excitatory amino acids (EAAs) to...
In spite of prompt diagnosis and either orchiectomy or preservation of the affected testis, infertility remains a significant sequel to testicular torsion. The objective of this study was to e...
The main goal of this study was to investigate the potential protective effects of enzymatic and nonenzymatic antioxidants on cryopreservation injuries to red deer epididymal spermatozoa. In Expe...
Testicular torsion followed by torsion repair induces an ischemia-reperfusion injury to the testis that can render the testis aspermatogenic. Previous results have demonstrated this loss of sp...
Clinical reproductive practice is often multivariate: multiple conditions in the male and/or female may coexist to confound diagnoses and therapeutic strategies. Given that treatment of an underlyin...
Dr Samuel Thompson poses a question regarding the use of electroejaculation in the management of an azoospermic patient who has anal stenonsis secondary to imperforate anus which was repaired as a neo...

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