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Age-related changes in the concentration of cytosolic androgen receptors in the epididymis, vas deferens and seminal vesicle of maturing male mice
Age-related changes cytosolic androgen receptors epididymis
2009/2/23
In this study, changes in the number of androgen binding sites that occur in cytosols of epididymis, vas deferens and seminal vesicle of mice from 10 to 90 days of age are described. Specific satura...
Evidence for age-dependent changes in Sertoli cell androgen receptor concentration
age-dependent changes Sertoli cell receptor concentration
2009/2/23
Cytosol and nuclear receptor concentrations in Sertoli cells isolated from the testes of 15-, 25-, and 35-day-old rats were measured using hydroxylapatite separation procedures. In these cells the m...
Decrease in the number of human Ap and Ad spermatogonia and in the Ap/ Ad ratio with advancing age. New data on the spermatogonial stem cell
human testis spermatogonia aging
2009/2/23
The numbers of Ap and Ad spermatogonia per unit section of the testis were calculated in autopsy specimens from young adults and elderly men without testicular pathology. The number of Ap spermatogo...
Age-related variation in seminiferous tubules in men. A stereologic evaluation
Age-related variation seminiferous tubules men
2009/2/23
Tubular boundary tissue and seminiferous epithelia were evaluated stereologically in testes from 28 men aged 20 to 48 years and 28 men aged 50 to 90 years. Testes obtained at autopsy within 15 hours...
Regulation of testicular ornithine decarboxylase in vitro. Effect of age, follicle-stimulating hormone, and luteinizing hormone
rat testis omithine decarboxylase aging
2009/2/19
We have examined hormonal regulation of ornithine decarboxylase (ODC) activity in decapsulated rat testis, isolated testicular interstitial cells, and purified Leydig cells under defined conditions ...
FSH Stimulation of cAMP Accumulation in Hamster Sertoli Cells：Effect of Age and Optic Enucleation
cAMP Sertoli cells hamsters optic enucleation
2009/2/19
Sertoli cells isolated from immature, adult, and adult optic-enucleated hamsters respond to FSH, but not to LH, with an increase in cAMP accumulation. There is an age-related decline in responsivene...
Prostatic growth rate determined from MRI data：age-related longitudinal changes
Prostatic growth rate MRI data age-related longitudinal changes
2009/2/18
Men with prostatic enlargement are at highest risk of developing symptomatic lower urinary tract symptoms (LUTS) and related outcomes, such as acute urinary retention. The study of prostatic growt...
Does age-associated reduced Leydig cell testosterone production in Brown Norway rats result from under-stimulation by luteinizing hormone?
Aging testis steroids rat
2009/2/18
Previous studies have shown that reductions in Leydig cell testosterone production occur with aging in the Brown Norway rat. The recent observation that changes in luteinizing hormone (LH) pulse i...
Age-related decreased Leydig cell testosterone production in the brown Norway rat
Aging Leydig cell testosterone LII Brown Norway
2009/2/13
Previous studies have demonstrated that Leydig cell testosterone production diminishes with age in Brown Norway rats. The objective of the studies presented herein was to test the following possible...
The origin and development of benign prostatic hyperplasia. An age-dependent process
prostatic hyperplasia age-dependent process
2009/2/7
Although the exact cause of benign prostatic hyperplasia (BPH) is not well defined, it is thought to occur as the result of epithelial-stromal interactions in the appropriate hormonal milieu. Beni...
Age as a factor influencing the power and sensitivity of experiments for assessing body weight, testis size, and spermatogenesis in rats
Experimental design daily sperm production spermatogenesis testes
2009/2/6
Data from 25 rats aged 60, 150, or 240 days (n = 75) were used to determine the number of observations per rat and or rats per treatment group needed to provide future experiments of known power and...
Age-related decrease in hypothalamic gonadotropin-releasing hormone（GnRH）gene expression, but not pituitary responsiveness to GnRH, in the male Brown Norway rat
Age-related decrease hypothalamic gonadotropin-releasing hormone（GnRH）gene expression pituitary responsiveness GnRH male
2008/12/25
As is the case in humans, aging male Brown Norway (BN) rats exhibit both primary and secondary (hypothalamic/pituitary) testicular failure. We hypothesized that secondary testicular failure in aging...
Semen and Sperm Reference Ranges for Men 45 Years of Age and Older
WHO reference values semen and sperm parameters reproductive hormones
2008/12/24
The most widely used reference values for human semen and sperm variables were developed by the World Health Organization (WHO) to help assess the fertility status of men interested in reproducti...
Age-Related Epididymis-Like Intratesticular Structures：Benign Lesions of Wolffian Origin That Can Be Misdiagnosed as Testicular Tumors
Testis rete testis cysts aging
2008/12/23
This study aims to characterize the epididymis-like intratesticular structures (ELITSs), a rare lesion found in elderly men. ELITSs were identified in 6 patients from a review of 1442 autopsies an...
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