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Role of the Hypothalamo-Pituitary-Adrenal Axis in the Modulation of Pollinosis Induced by Pollen Antigens
ACTH HPA axis IgE pollinosis stress
2010/11/12
The present findings show that the HPA-axis and ACTH play important roles in the regulation of plasma cytokines and IgE thereby modulating symptoms of pollinosis. The results also suggest that a mild ...
Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis
diet therapy flavonoid Japanese cedar pollen pollinosis quercetin
2010/11/16
During the entire study period, ocular symptom + medication score for the EMIQ group was significantly lower (p < 0.05) than that of the placebo group. When limited to the period, ocular symptom score...
Patterns of Drug Prescription for Japanese Cedar Pollinosis Using a Clinical Vignette Questionnaire
allergic rhinitis guideline Japan physician's practice patterns questionnaires
2010/11/17
Our investigation suggested that, compared to ENTs, GPs and IMs have a lower tendency to concomitantly prescribe drugs for localized treatment such as nasal corticosteroids and eye drops with oral med...
Enhanced Production of IgE Anti-Japanese Cedar Pollen Specific Antibodies by Peripheral Blood B Cells from Patients with Japanese Cedar Pollinosis
B cells class switching ELISA immobilized anti-CD3 Japanese cedar pollen
2010/11/17
Background: IgE antibodies against Japanese cedar pollen (JCP) play an important role for the pathogenesis of the cedar pollinosis, but the mechanism of their production has been unclear. We explored ...
Immunologic determination of the major allergen, Cry j 1, in Cryptomeria japonica pollen of 117 clones in Toyama prefecture: Some implications for further forestry research in pollinosis prevention
Cry j 1 Cryptomeria japonica D. Don environmental factor genotype variation Japanese cedar pollinosis
2010/11/24
Background: A number of recent studies have clarified the characteristics of major allergens of Cryptomeria japonica, such as the locality, molecular weights of Cry j 1 and Cry j 2 and cross-reactivit...
Non-IgE,-IgG4 Antibody to Japanese Cedar Pollen Allergens: Comparison of Its Prevalence and Titers between Pollinosis Patients and Non-Patients
IgG4 antibody in non-patients Japanese cedar pollinosis non-IgE reverse-sandwich ELISA
2010/11/19
We detected specific non-IgE,-IgG4 in both the patients and non-patients. In comparison to the IgE antibody, which was detected in a small proportion of the non-patients with low titers, the non-IgE,-...
Clinical aspects of Japanese cedar pollinosis
Japanese cedar pollinosis management pollen survey prevalence risk factor
2010/11/29
Japanese cedar pollinosis (JCPsis) is a major national health problem in Japan. The present review provides an update on information on JCPsis based on clinical data from our research group, through t...