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Absence of Nasal Blockage in a Japanese Cedar Pollen-Induced Allergic Rhinitis Model Mouse
allergic rhinitis animal model cedar pollen nasal blockage sneezing
2010/11/16
The serum Cry j 1-specific IgE level showed clear elevation only in the group sensitized by Cry j 1 + Al(OH)3 and then challenged by Cry j 1. No elevations were seen in the groups sensitized by pollen...
Relationship between Exhaled Nitric Oxide Measured by Two Offline Methods and Bronchial Hyperresponsiveness in Japanese Adults with Asthma
asthma bronchial hyperresponsiveness exhaled nitric oxide offline method
2010/11/17
Levels of eNOs and eNOc were correlated with the degree of bronchial hyperresponsiveness to acetylcholine in adult asthmatics treated with inhaled corticosteroids. Our findings suggest that offline mo...
Effect of Cry-consensus Peptide, a Novel Recombinant Peptide for Immunotherapy of Japanese Cedar Pollinosis, on an Experimental Allergic Rhinitis Model in B10.S Mice
allergic rhinitis Cry j 1 Cry j 2 Japanese cedar pollinosis T-cell epitope
2010/11/18
Cry-consensus peptide markedly inhibited Cry j 1-induced sneezes, eosinophil infiltration, and eosinophil peroxidase (EPO) activity in nasal tissue. Cry-consensus peptide inhibited the production of a...
Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients
allergic rhinitis cedar pollinosis daily life fexofenadine quality of life
2010/11/22
Background: The aim of the present survey was to investigate the changes associated with fexofenadine administration in the quality of life (QOL) of Japanese cedar pollinosis patients.
Methods: After...
HLA class II association with Type I allergy to house dust mite and Japanese cedar pollen in Japanese subjects
allergic rhinitis HLA class II HLA oligotyping PCR-SSO Type I allergy
2010/11/29
We evaluated the incidence of the association of HLA class II phenotype and specific IgE responsiveness against house dust mite (HDM) and/or Japanese cedar pollen (Jc) in 176 patients with allergic rh...