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Antigen-Specific Immunotherapy against Allergic Rhinitis: The State of the Art
allergic rhinitis biomarker immunotherapy pollinosis regulatory T cell
2010/11/12
Allergic rhinitis is the most prevalent type I allergy in industrialized countries. Pollen scattering from trees or grasses often induces seasonal allergic rhinitis, which is known as pollinosis or ha...
Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
allergic rhinitis chemical mediators guinea pigs olopatadine
2010/11/25
Background: Various mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the m...
Influence of local antigen exposure dose in the upper respiratory tract on sensitization with cedar pollen
cedar pollen IgE laryngeal allergy pollinosis
2010/11/24
The mean serum levels of specific IgE antibody in rats exposed to the higher dose were significantly higher than those in rats exposed to the lower dose, and the mean levels in rats in the lower-dose ...
Repeated antigen challenge in patients with perennial allergic rhinitis to house dust mites
nasal provocation test perennial allergic rhinitis priming effect repeated antigen challenge
2010/11/24
In contrast with pollinosis, nasal provocation reactions were not clearly enhanced by repeated provocation. To further understand nasal reactions induced by antigen challenge, studies should be perfor...
Time-course changes in nasal airway resistance after house dust antigen challenge: With special reference to late phase response
antigen challenge basophilic cells eosinophil house dust mite late phase response nasal airway resistance perennial nasal allergy
2010/11/29
The definition of late-phase response (LPR) associated with nasal allergy is not as clear as that associated with asthma. Furthermore, LPR and immediate-phase response often act in concert to produce ...