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2023年5月8日,中国科学院上海营养与健康研究所胡国宏研究员受邀在国际知名学术期刊Cancer Cell上发表题为“A genetic portrait of metastatic seeds in lung adenocarcinoma”的专评文章,对该刊同期发表的一项题为“Genomic mapping of metastatic organotropism in lung adenocar...
肝损伤和细胞死亡是所有肝脏疾病的共同特征。肝移植是终末期肝病的一种既定的治疗方法。然而,由于器官移植的技术特征,肝移植过程中的缺血/再灌注损伤(Hepatic ischemia-reperfusion,I/R)是肝脏外科手术过程中最具有挑战性的问题之一,其可诱发肝细胞损伤进而导致严重的细胞死亡。铁死亡(ferroptosis)作为一种铁离子依赖的新型细胞程序性死亡,以铁稳态(iron homeos...
The presence of alloreactive memory T cells in recipient is a critical handicap to achieving transplantation tolerance. To make a mouse model that can as closely as possible mimic the presensitized tr...
Summary Memory T cells are known to play a key role in prevention of allograft tolerance in alloantigen-primed mice. Here, we used an adoptively transferred memory T cell model and an alloantigen-prim...
Hemopoietic stem cell transplantation is being carried out for rapidly increasing numbers of patients. Survival probabilities have increased progressively, and most patients return to productive lives...
The hematopoietic stem cell transplant activity survey of the European Group for Blood and Marrow Transplantation (EBMT) represents a novel modern tool in health care management. Introduced in 1990, ...
Background: Myeloablative-allogeneic stem cell transplantation is a common way of treating various malignant and nonma-lignant diseases; but, it is associated with hazardous immediate and late complic...

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