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Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
抑制缝隙连接预防药物性肝毒性和爆发性肝功能衰竭(Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure)
抑制缝隙 预防药物性 肝毒性 爆发性 肝功能衰竭
2012/2/1
Drug-induced liver injury (DILI) limits the development and application of many therapeutic compounds and presents major challenges to the pharmaceutical industry and clinical medicine. Acetaminophen-...
期刊信息
篇名
Amiloride inhibition of glycinergic mIPSCs in mechanically dissociated rat spinal neurons
语种
英文
撰写或编译
作者
Li Y,Li YF,Xu TL
第一作者单位
刊物名称
Neuroscience Letter
页面
2003, 349:17-20
出版日期
2003年
月
日
文章标识...
期刊信息
篇名
Inhibition of glycine response by amiloride in rat spinal neurons
语种
英文
撰写或编译
作者
Li YF,Li Y,Xu TL
第一作者单位
刊物名称
Neuroscience Letter
页面
2003, 345:173-176
出版日期
2003年
月
日
文章标识(ISSN)
相关项目
GABAa受体与甘氨...
Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons
2007/7/28
期刊信息
篇名
Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons
语种
英文
撰写或编译
作者
Li Y,Wu LJ,Legendre P,Xu TL
第一作者单位
刊物名称
Journal of Biological Chemistry
页面
2003...