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Immunological Tolerance: Therapeutic Induction
免疫耐受诱导 Immunological Tolerance: Therapeutic Induction
2014/6/24
Protection from the development of autoimmune diseases and acceptance of transplanted organs are due to effective tolerance to self-antigens and alloantigens, respectively. Various immunological strat...
Immunological tolerance refers to a reduction or complete inhibition of the ability of an individual to mount a specific immune response upon immunization.
Introduction of an exogenous antigen into the fetus at the time of repertoire maturation renders the host’s immune system tolerant to that antigen. This view stems from a historical observation of non...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...