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Mandibular necrosis in beagle dogs treated with bisphosphonates
osteonecrosis bisphosphonates
2014/12/4
Objectives – To test the effect of bisphosphonate (BP) treatment for up to 3 years on bone necrosis and osteocyte death in the mandible using a canine model. Materials and Methods –...
Mandible matrix necrosis in beagle dogs After 3-years of daily oral bisphosphonate treatment
osteonecrosis of the jaw remodeling suppression
2014/12/4
Purpose An increasing number of reports have implicated bisphosphonates as contributing to osteonecrosis of the jaw. The goal of this study was to evaluate mandible necrosis in beagle dogs treated for...
Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...