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Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs
airway hyperresponsiveness bradykinin cationic protein low molecular weight heparin poly-L-lysine 6-keto-PGF1α thromboxane A2
2010/11/26
To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the b...
Adrenomedullin stimulates cyclic AMP production in the airway epithelial cells of guinea-pigs and in the human epithelial cell line
adrenomedullin airway cAMP epithelial cell guinea-pig human
2010/11/26
This study was designed to examine the effects of adrenomedullin (AM) on airway epithelial cells. Primary cultures of guinea-pig tracheal epithelial cells and the human bronchiolar epithelial cell lin...
Effect of histamine H1 receptor antagonists on antigen-induced increase of cough sensitivity in guinea pigs
allergic reaction capsaicin cough sensitivity guinea pig histamine H1 receptor antagonists
2010/11/26
Eosinophilic airway inflammation and increased cough sensitivity without bronchial hyperresponsiveness are the pathologic and physiologic features of bronchodilator-resistant non-productive cough-asso...
Airway responsiveness to acetylcholine or capsaicin in immature and mature guinea pigs in vivo
aging airway obstruction asthma capsaicin neuropeptide
2010/11/25
Non-specific airway hyperresponsiveness is a characteristic feature of bronchial asthma. Airway reactivity to cholinergics may change with age during childhood. The present paper describes tests to se...