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Caloric Restriction and Formalin-Induced Inflammation:An Experimental Study in Rat Model
Caloric Restriction Inflammation Animal Models Iran
2015/11/9
Background: Acute and chronic inflammations are difficult to control. Using chemical anti-inflammatory medications along with their complications considerably limit their use. According to Traditional...
The Effect of Estrogen Usage on Eccentric Exercise-Induced Damage in Rat Testes
Exercise Testis Estrogens Rats
2015/10/22
Background: Recent years, lots of scientific studies are focused on the possible mechanism of inflammatory response and oxidative stress which are the mechanism related with tissue damage and exercise...
NONINVASIVE MONITORING OF CCl4 INDUCED ACUTE AND CHRONIC LIVER DAMAGE IN RAT BY SINGLE QUANTUM AND TRIPLE QUANTUM FILTERED 23Na MAGNETIC RESONANCE IMAGING
liver damage carbon tetrachloride rat model
2015/5/22
In present study, single quantum (SQ) and triple quantum filtered (TQF) 23Na magnetic resonance imaging (MRI) was used to monitor the severity and progression of CCl4 induced acute and chronic liver d...
Field fever, harvest fever, rat catcher's yellows: Leptospirosis by any name is a serious disease
Field fever harvest fever rat catcher's yellows Leptospirosis any name
2015/3/4
The following is part 14 in a series on the NSF-NIH-USDA Ecology and Evolution of Infectious Diseases (EEID) Program. See parts:one,two,three, four, five, six, seven, eight,&#...
Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
rodent modeling and remodeling osteoblast
2014/12/4
Recent studies demonstrate that bisphosphonates suppress bone resorption by leading to apoptosis of the osteoclast and inhibiting the differentiation to mature osteoclasts. The influence of bisphospho...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM tension nanoscale
2014/12/4
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
The Effects of Insulin-Like Growth Factor-1 Gene Therapy and Cell Transplantation on Rat Acute Wound Model
IGF-1 Gene Therapy Cell Transplantation Fibroblast Wound Healing
2015/10/15
Background: Wound healing is a complex process. Different types of skin cells, extracellular matrix and variety of growth factors are involved in wound healing. The use of recombinant growth factors i...
Effects of Losartan and Vanillic Acid Co-Administration on Ischemia-Reperfusion-Induced Oxidative Stress in Isolated Rat Heart
Oxidative Stress Injury Vanillic Acid Losartan
2015/10/13
Background: Experimental studies have demonstrated that angiotensin II (ANG-II)-induced oxidative stress contributes to the pathogenesis of I/R injury.
Effects of Gallic Acid and Cyclosporine A on Antioxidant Capacity and Cardiac Markers of Rat Isolated Heart After Ischemia/Reperfusion
Antioxidant Capacity Cyclosporine A Ischemia Reperfusion Gallic Acid Myocardial Infarction
2015/10/13
Background: Myocardial infarction is one of the important causes of death during old ages. Gallic acid as an antioxidant or cyclosporine A (CsA) as inhibitor of mitochondrial permeability transition p...
Effect of Pentoxifylline Administration on Mast Cell Numbers and Degranulation in a Diabetic and Normoglycemic rat Model Wound Healing
Pentoxifylline Mast cells Diabetes Mellitus Wound Healing
2015/9/28
Background: Wound healing is a complicated and integrated process. Researches in the molecular level on human and animal models have indicated several molecular changes related to the effect of diabet...
Anti-Inflammatory Effect of Oleuropein in Experimental Rat Spinal Cord Trauma
Oleuropein Spinal cord Trauma Inflammation Rat
2015/9/25
Background: Spinal cord injury stimulates an inflammatory reaction that causes substantial secondary damage inside the injured spinal tissue. The purpose of this study was to determine the anti-inflam...
Effect of Exercise on Diabetes-Induced Oxidative Stress in the Rat Hippocampus
Oxidation Stress Diabetes Treadmill Exercise Apoptosis Hippocampus
2015/9/25
Background: Oxidative stress forms the foundation for the induction of multiple cellular pathways which can lead to the complications of diabetes mellitus that the most debilitating ones are diseases ...
Thioacetamide-Induced Acute Hepatic Encephalopathy in Rat: Behavioral, Biochemical and Histological Changes
Acute hepatic encephalopathy Thioacetamide Rat
2015/9/25
Background: As a serious neuropsychiatric disease, hepatic encephalopathy (HE) is a clinical condition with several types regarding chronicity and clinical diversity that can develop as a complication...
Effects of kirenol on bovine type II collagen-induced rat lymphocytes in vivo and in vitro
奇壬醇 II型胶原 淋巴细胞 类风湿性关节炎
2012/4/24
目的观察奇壬醇对牛II 型胶原特异性淋巴细胞体内和体外的免疫调节作用，探讨奇壬醇对抗原特异性淋巴细胞的免疫抑制作用机制。方法将Wistar 大鼠随机分为对照组、模型组、奇壬醇组和泼尼松龙组。除对照组外，均复制胶原诱导关节炎大鼠模型，造模当天开始给药。造模30 d 后取脾脏和引流淋巴结，制备单细胞悬液，经体外培养48 h 后，ELISA法检测培养上清中干扰素-γ（IFN-γ）、白介素-10（IL-1...
Caustic esophageal injury decreases the number of interstitial cells of Cajal in the rat esophagus
Caustic esophageal injury interstitial cells of Cajal esophagus
2010/10/14
To evaluate the effect of caustic esophageal injury (CEI) on the number of interstitial cells of Cajal (ICC). Materials and methods: Wistar rats were divided into 3 groups: control, acid, and alkali i...