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Background: Zoonotic Cutaneous Leishmaniasis (ZCL) is an endemic health problem in many rural areas of Iran, with doubled number of incidences over the last decade. Different species of rodents serve ...
Stage-specifci developmental forms of Lesihmania major promastigotes were grown in vitro. Procyclic and metacyclic promastigotes were cultured and separated by peanut agglutinin. The axenic amastigote...
The susceptibility of various strains of mice to infection by Leishmania tropica (major) was recently studied in this laboratory. The infection in A/J, C3H, CBA, AKR/J, AKR/CU, and C57B1 mice (the sem...
Background: The aim of this study was to assess Leishmania infection in sand fly species from areas where leishmaniasis is endemic. This is important for prediction of the risk and expansion of the di...
Background: Determination of the division history of T cells in vitro is helpful in the study of effector mechanisms against infections. Technique described here uses the intracellular fluorescent lab...
Background: To compare the pathogenicity differences in two susceptible Balb/c and resistant C57bl/6 mice infected with Leishmania major MRHO/IR/75/ER as a prevalent strain of zoonotic cutaneous leish...
Background: Cutaneous leishmaniasis is an important health problem caused by Leishmania spp. As there is no vaccine, drug treatment is the only way to tackle leishmaniasis. In the present study, inhib...
Aim: Infections caused by protozoa of the genus Leishmania are major worldwide health problems with high endemicity in developing countries. The incidence of leishmaniasis has increased in the absence...
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...
Visceral Leishmaniasis (Kala-azar) is a serious health problem in some northern and south western parts of Iran. The incidence of kala-azar caused by Leishmania infantum has recently increased in Nour...
Reports from the health center of Kerman Province, southern Iran showed an increasing of cutaneous leishmaniasis cases in Orzuieh Rural District, southwest of the province in 2003. The report encourag...
Background: Dogs have been previously reported to be reservoirs of Leishmania infantum as the etiological agent of human visceral leishmaniasis in Iran. We report a case of canine visceral leishmanias...
BALB/c mice are highly susceptible to infection with the protozoan parasite Leishmania major. This susceptibility has been attributed in part to the expansion of Th2 cells and production of their cyto...
In this study, a crude leishmanial antigen, was prepared by sonicating Leishmania major promastigotes used to induce immunity in BALB/c mice against cutaneous leishmaniasis. Correlation between the ro...

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