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Expression and Clinical Significance of Tumor Necrosis Factor Receptor-Associated Factor 6 in Patients With Colon Cancer
Receptors Tumor Necrosis Factor Gene Expression Colonic Neoplasms
2016/1/26
Background: Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been reported to be highly expressed in many tumor tissues, but it is still of value to detect its expression in patients wit...
Tumor Necrosis Factor-Alpha Polymorphism and Susceptibility to Multiple Sclerosis in the Iranian Population
Tumor Necrosis Factor-Alpha Multiple Sclerosis Sclerosis
2015/10/16
Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to play an important r...
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Tumor Necrosis Factor-Alpha Polymorphism at Position -238 in Preeclampsia
Tumor Necrosis Factor-Alpha Pre-Eclampsia Polymorphism Genetic
2015/10/10
Background:: Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines and their expression rema...
Interleukin-12 and Tumor Necrosis Factor-Β Gene Polymorphisms as Genetic Susceptibility Factors for Brucellosis in Iranian Patients
Brucella Genetic polymorphisms Interleukin-12 Tumor necrosis factor-β Iran
2015/9/21
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Current status of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) targeting cancer therapy
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) TRAIL receptor 1 (TRAIL-R1), TRAIL receptor 2 (TRAIL-R2) apoptosis KM mouseTM monoclonal antibody targeting therapeutics
2009/7/15
Monoclonal antibodies have already established a secure position as a very promising strategy for anti-tumor therapeutics. High specificity and high affinity are attractive characteristics of antibodi...
Tumor Necrosis Factor-a and Interleukin-6 in Peritoneal Adhesion Formation
Peritoneal adhesion Tumor necrosis factor-a Interleukin-6
2009/7/2
This study was carried out to assess the role of tumor necrosis factor (TNF-a) and interleukin-6 (IL-6 ) in plasma and peritoneal fluid in higher rates of adhesion formation following standard bowel i...
Development of ELISA Systems for Measurement of Human Tumor Necrosis Factor-Alpha (TNF-a)
TNF-a,ELISA
2009/6/22
The aim of this study was to develop a human tumor necrosis factor alpha (hTNF-a) ELISA system because specific and sensitive measurement of low levels of circulating TNF-a is very important for enlig...
Relationship between tumor necrosis factor-alpha (TNF) profile and urinary tract pathology in rural Nigerians with Schistosoma haematobium infection
Schistosoma haematobium Tumor necrosis factor
2010/12/10
Schistosomiasis is estimated to affect more than 200 million people especially in rural and agricultural areas. Schistosoma haematobium causes significant urinary tract diseases and is mediated by T c...
The Effects of Dibutyltin(DBT)Dichloride on the Viability and the Productions of Tumor Necrosis Factor α and Interleukin-12 in Murine Macrophage Cell Line, J774.1.
dibutyltin macrophages interleukin-10 interleukin-12
2009/3/16
Immunotoxicity is one of toxic effects of dibutyltin(DBT)compounds. In our previous study, the inhibitory effects of DBT on the productions of tumor necrosis a(TNFα)and interleukin-1β in a murine macr...
Inhibition of chlamydia trachomatis growth by human interferon-α：mechanisms and synergistic effect with interferon-γ and tumor necrosis factor-α
chlamydia trachomatis growth human interferon-α synergistic effect interferon-γ and tumor necrosis factor-α
2009/3/3
We have evaluated the effect of natural human interferon (IFN)-α on the growth of chlamydia trachomatis in human epithelial cells in vitro and revealed that IFN-α has reduced both growth and infecti...
The effect of tumor necrosis factor on human sperm motility in vitro
tumor necrosis factor human sperm motility
2009/2/23
Tumor necrosis factor (TNF alpha) is present in elevated levels in peritoneal fluid from infertile women with endometriosis. The effect of TNF alpha on human sperm motility in vitro was evaluated ...
Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells
murine interleukin-2 gamma interferon tumor necrosis factor testosterone synthesis
2009/2/11
It was recently observed that treatment of patients with a high dosage of human interleukin (IL-2) resulted in suppression of plasma concentrations of testosterone. A murine model was developed to a...
The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro
Tumor necrosis factor interleukin-1 interferon human sperm motility
2009/2/10
Whether cytokines present in human peritoneal fluid reduce sperm motility, and thus contribute to infertility, is investigated. The human recombinant cytokines, tumor necrosis factor-alpha, interl...
Tumor necrosis factor and interleukin-1 stimulate testosterone secretion in adult male rat Leydig cells in vitro
umor necrosis factor interleukin-1 testis testosterone
2009/2/6
The actions of two cytokines, tumor necrosis factor (TNF) and interleukin-1 (IL-1), on testosterone production by dispersed adult testis cells and purified Leydig cells in culture were studied. In o...