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探讨温针灸对骨关节炎(OA)大鼠软骨组织Clock、Bmal1蛋白表达的影响。方法 60只3月龄SPF级雄性SD大鼠,按随机数字表法分为对照组、模型组、针刺组、温针灸组,每组15只。以手术方法制备OA大鼠,温针灸组于造模第1天取足三里、犊鼻和内膝眼穴温针灸治疗,采用手针及悬灸法,15 min/次,1次/天,共21天。针刺组采用针刺方法同温针灸组,不用艾灸。对照组大鼠自由饮水,正常饲养。所有大鼠于相...
The Autonomic Function around the Clock.
Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity
Genetic variants susceptibility
2016/12/30
Lean (n = 715) and overweight or obese (n = 391) unrelated subjects aged 34.4 ± 8.6 y were included in a population-based cross-sectional study. Six tag single-nucleotide polymorphisms (SNPs) with a m...