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Assessment of iron status in settings of inflammation: challenges and potential approaches
infection inflammation iron status preschool children serum ferritin soluble transferrin receptor total-body iron stores women of reproductive age
2018/11/21
The determination of iron status is challenging when concomitant infection and inflammation are present because of confounding effects of the acute-phase response on the interpretation of most iron in...
Inflammatory potential of the diet and colorectal tumor risk in persons with Lynch syndrome
adapted dietary inflammatory index colorectal adenoma
2018/11/20
Background: Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair (MMR) genes. An important pro...
X-Ray Study Reveals Long-Sought Insights Into Potential Drug Target
X-Ray Long-Sought Insights Potential Drug Target
2017/4/27
X-ray studies done in part at the Department of Energy’s SLAC National Accelerator Laboratory have produced surprising insights into the workings of a hormone receptor associated with blood pressure r...
Continuous renal replacement therapy: a potential source of calories in the critically ill
nutrition CRRT CVVH citrate anticoagulation caloric uptake
2018/11/14
Background: Overfeeding can lead to multiple metabolic and clinical complications and has been associated with increased mortality in the critically ill. Continuous venovenous hemofiltration (CVVH) re...
2016冷泉港学术会议:基础免疫学及其治疗潜力(Cold Spring Harbor conference on Fundamental Immunology & Its Therapeutic Potential)
Fundamental Immunology Therapeutic Potential
2017/1/19
We are pleased to announce the 2nd Cold Spring Harbor meeting on Fundamental Immunology & Its Therapeutic Potential, which will begin on Tuesday evening, April 25 and end at noon on Saturday, April 29...
Estimating the reliability of glycemic index values and potential sources of methodological and biological variability
glycemic index variability healthy volunteers insulin index glycated hemoglobin
2018/12/14
Background: The utility of glycemic index (GI) values for chronic disease risk management remains controversial. Although absolute GI value determinations for individual foods have been shown to vary ...
Flavonoids: a review of probable mechanisms of action and potential applications
Flavonoids bioflavonoids antioxidants
2016/6/14
The aim of this review, a summary of the putative
biological actions of flavonoids, was to obtain a further
understanding of the reported beneficial health effects of these
substances. Flavonoids o...
Functional foods as a marketing term was initiated
in Japan in the late 1980s and is used to describe foods fortified
with ingredients capable of producing health benefits. This
concept is becoming...
Receptor-mediated signaling pathways: potential targets of modulation by dietary fatty acids
dietary fat tyrosine kinase protein kinase
2016/6/1
Extracellular signals are transmitted to intracellular
targets through many signal-transduction pathways. Each
signaling pathway is composed of a network of interacting signaling
molecules that reg...
Potential interventions for the prevention of childhood pneumonia in developing countries: improving nutrition
Protein-energy malnutrition birth weigh pneumonia
2016/6/1
Acute respiratory infections are the leading
cause of childhood death in developing countries. Current efforts
at mortality control focus on case management and immunization,
but other preventive s...
Energy metabolism in African Americans: potential risk factors for obesity
Ethnicity metabolic rate respiratory quotient
2016/5/31
Recent reports have identified a lower resting
metabolic rate in African Americans than in whites, but most
studies included only females and used short-term measurements
with ventilated-hood syste...
Potential mechanisms of metabolic imprinting that lead to chronic disease
early nutrition chronic disease obesity
2016/5/30
This review synthesizes a subset of human epidemiologic
and experimental animal studies that suggest that
early nutrition affects susceptibility to chronic diseases in adulthood.
These studies prov...
Dysphagia in the high-risk infant: potential factors and mechanisms
dysphagia feeding disorders neonate dysphagia feeding disorders neonate aerodigestive reflexes gastroesophageal reflux
2018/11/28
Neonatal dysphagia, or abnormalities of swallowing, represent a major global problem, and consequences of dysfunctional feeding patterns carry over into infancy and toddler age groups. Growth, develop...