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A serendipitous finding lends new insight into how atopic dermatitis develops（图）
特应性皮炎 皮肤病 皮肤
2023/7/12
Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a ne...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
New Therapy Using Omega-3-Acid Ethyl Esters for Decubitus Ulcers and Stasis Dermatitis:A Case Report
Omega-3 Fatty Acids Ethyl-Eicosapentaenoic Acid Docosahexaenoic Acid Ethyl Ester Pressure Ulcers
2015/10/16
Introduction: In daily practice, it is common to experience difficulty in treating decubitus ulcers (pressure ulcers, also known as decubitus ulcers) and stasis dermatitis of the lower limbs. We hereb...
Bullous Dermatitis Artefacta in a 17 Year-old Girl Induced by a Native Herb
Dermatitis Factitious Disorders Bollous lesions
2015/10/8
Dermatitis artifacta is a factitious dermatological disorder with many forms of presentation of self inflicted skin lesions in any part of the body. Dermatitis artefacta is a difficult condition for d...
A 32-year-old man was attacked by flies while camping around Khorram Abad, Lorestan Province, western Iran. Pruritic dermatitis with marked edema and considerable discomfort appeared mainly on the low...
Face and Neck Dermatitis from a Stainless Steel Orthodontic Appliance
Nickel allergy Orthodontics
2010/3/9
Although nickel is the most common cause of contact allergy, nickel-containing orthodontic appliances seldom cause adverse reactions that result in discontinuation of treatment. We report on an erupti...
Elevated Platelet Activation in Patients with Atopic Dermatitis and Psoriasis: Increased Plasma Levels of β-Thromboglobulin and Platelet Factor 4
atopic dermatitis platelet factor 4 platelets psoriasis β-thromboglobulin
2010/11/17
Our results show that blood platelets are activated in patients with AD or psoriasis, suggesting that activated platelets play a role in the pathomechanism of chronic skin inflammation. Furthermore, p...
Genetic Susceptibility to Atopic Dermatitis
atopic dermatitis epidemiology genetic polymorphism
2010/11/17
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with an increasing prevalence in industrialized countries. AD belongs to the group of allergic disorders that includes food allergy, alle...
DISABLING WORK-RELATED PERSISTENT PHOTOSENSITIVITY FOLLOWING PHOTOALLERGIC CONTACT DERMATITIS FROM CHLORPROMAZINE AND OLAQUINDOX IN A PIG BREEDER
agricultural workers’ disease pig breeder chlorpromazine olaquindox
2010/12/23
The use of veterinary medicines and medicated feed has a potential for the exposure of agricultural workers to pharmaceuticals with phototoxic and photoallergic sideeffects.
Urinary Eosinophil-derived Neurotoxin Concentrations in Patients with Atopic Dermatitis: A Useful Clinical Marker for Disease Activity
atopic dermatitis eosinophil eosinophil-derived neurotoxin visual analogue scale
2010/11/18
Background: It has been reported that measurements of eosinophil-derived neurotoxin (EDN) may be useful for identifying eosinophil activities in allergic diseases including atopic dermatitis.
Methods...
An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases
allergen atopic dermatitis mite Tec Th2
2010/11/18
We established a highly efficient, highly reproducible protocol to induce skin lesions in NC/Nga mice and successfully applied it to show the efficacy of terreic acid in treating skin lesions. This mo...
Suplatast/Tacrolimus Combination Therapy for Refractory Facial Erythema in Adult Patients with Atopic Dermatitis—A Meta-Analysis Study—
atopic dermatitis erythema meta-analysis suplatast tacrolimus
2010/11/18
Background: Combination of suplatast tosilate with tacrolimus ointment was reported to reduce the dose of tacrolimus ointment with maintained treatment efficacy for refractory facial erythema in atopi...
A Novel Atopic Dermatitis Model Induced by Topical Application with Dermatophagoides Farinae Extract in NC/Nga Mice
animal model atopic dermatitis Dermatophagoides farinae house dust mite NC/Nga mice
2010/11/18
Repeated application of Df extract ointment caused rapid increase in dermatitis scores. Clinical (skin dryness, erythema, edema and erosion) and histological symptoms (dermal and epidermal thickening,...
Dietary Whey Protein Hydrolysate Suppresses Development of Atopic Dermatitis-like Skin Lesions Induced by Mite Antigen in NC/Nga Mice
atopic dermatitis Dermatophagoides pteronyssinus E-selectin mice whey protein
2010/11/18
Background: Oral administration of enzymatic hydrolysate of cow's milk whey protein (WPH) has been reported to produce an anti-inflammatory effect. Since inflammation plays a role in dermatitis of all...
Anti-allergic effect of apple polyphenol on patients with atopic dermatitis: A pilot study
anti-allergic effect apple polyphenol atopic dermatitis
2010/11/25
The aim of the present study was to evaluate the anti-allergic effect of apple condensed tannins (ACT) in patients with atopic dermatitis (AD) as a pilot study. An ACT supplement given to the patients...