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Receptors found on cell surfaces bind to hormones, proteins, and other molecules, helping cells respond to their environment. MIT chemists have now discovered how one of these receptors changes its sh...
For a cell to grow and divide, it needs to produce new proteins. This also applies to cancer cells. Researchers have now investigated the protein eIF4A3 and its role in the growth of cancer cells. The...
Proliferation of cells represents one of the most fundamental biological processes. The core cell cycle machinery that drives cell proliferation has been conserved from yeast to humans. Proper spatial...
Preventing pathological ocular angiogenesis is key to treating retinopathy of prematurity, diabetic retinopathy and age-related macular degeneration. At present there is no small molecule drug on the ...
Immobilized patterns of unmodified fibroblast growth factor-2 (FGF-2), with varying surface concentrations, were inkjet printed onto physiologically relevant fibrin substrates. Printed patterns were ...
We have investigated the effects on cultured cells of high pressure separately and combined with vanadate. Growth of Chinese hamster ovary cells was reduced at pressure above 75 bar; the reduction was...
The efficacy of antioxidant supplementation in the prevention of cardiovascular disease appears equivocal, however the use of more potent antioxidant combinations than those traditionally used may exe...
Transglutaminase 2 (TG2) is implicated in the inhibitory regulation of the hepatocyte growth in vitro. In vivo, however, the role of TG2 in liver regeneration after partial hepatectomy (PH) is almos...
Androgens via the androgen receptor (AR) play crucial roles in prostate physiology and pathophysiology. These androgen actions can be either inhibited or potentiated by estrogens. The mechanisms of ...
Thiiodothyronine (T3) plays an important role in the regulation of cell growth and differentiation. In this study, we show the different effects of T3 on cell growth response and expression of the t...

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