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Mutation in the RPE65 gene causing hereditary retinal dystrophy in the Briard dogs: application of a new detection method
RPE65 gene CSNB dog Briard electrophoresis
2015/6/5
Inherited eye diseases are widespread in most of the pure dog breeds and they show a severe impact on canine health, welfare and working ability. Congenital stationary night blindness (CSNB) was origi...
摘要
以绵羊BMP15基因和BMPR-IB基因为候选基因，以湖羊、中国美利奴单胎品系、中国美利奴肉用和毛用多胎品系为研究对象，采用PCR-RFLP方法对候选基因进行单核苷酸多态性（SNP）位点检测和基因型分析，同时研究基因对绵羊产羔数的影响。对BMP15基因进行SNP检测，结果未发现多态性位点；对BMPR-IB基因进行多态性检测，结果发现了一个A746 G SNP位点。依据A746 G SNP位...