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Tudor Domain Containing Protein TDRD12 Expresses at the Acrosome of Spermatids in Mouse Testis
Tdrd12 Tudor Spermatogenesis Acrosome Spermatid Testis
2016/7/27
Tdrd12 is one of tudor domain containing (Tdrd) family members. However, the expression pattern of Tdrd12 has not been well studied. To compare the expression levels of Tdrd12 in various tissues, real...
Disruptions to embryonic reprogramming alter adult mouse behavior
embryonic reprogramming adult mouse
2016/2/22
Right after fertilization, embryos at the earliest stages of development tell their genes: "Forget what it was like in the sperm or egg where you came from."
When the process of epigenetic reprogramm...
Characterization of Bovine NANOG5′-flanking Region during Differentiation of Mouse Embryonic Stem Cells
Bovine Embryonic Stem Cell NANOG Promoter Neural Differentiation Adipocyte Differentiation
2016/5/19
Embryonic stem cells (ESCs) have been used as a powerful tool for research including gene manipulated animal models and the study of developmental gene regulation. Among the critical regulatory factor...
Examination of Sexually Dimorphic Cell Death in the Pubertal Mouse Brain
Sexually Dimorphic Cell Death Pubertal Mouse Brain
2014/12/12
A period of cell death during a critical period early in life is responsible for causing permanent structural changes to many brain areas, but it is not known whether cell death plays a role in brain ...
Sex Difference in Calbindin Cell Number in the Mouse Preoptic Area: Effects of Neonatal Estradiol and Bax Gene Deletion
Sex Difference Calbindin Cell Number Mouse Preoptic Area Neonatal Estradiol Bax Gene Deletion
2014/12/12
The sexually dimorphic nucleus of the preoptic area (SDN-POA) was first discovered in rats and is one of the most famous and best studied sex differences in the field of neuroscience. Though well docu...
CHARACTERIZATION OF Ca2+ INFLUX PATHWAY(S) DURING MOUSE OOCYTE MATURATION
Calcium influx oocyte maturation SOCE Stim1 Phosphorylation
2014/12/10
Ca2+ signaling induced at fertilization, also known as oscillations, is essential in mammalian eggs to initiate early embryonic development. The generation of the oscillations relies on optimization o...
THE ESTRADIOL-INDUCED TRANSCRIPTOME OF THE FEMALE MOUSE ANTEROVENTRAL PERIVENTRICULAR NUCLEUS: MORE THAN JUST A KISS
Estrogen AVPV Ets2 Pdcd4 Kiss1 Ovulation
2014/12/10
Estradiol (E2) is critical in the reproductive mechanisms of mammals. In female rodents E2 acts through the neurons of the anteroventral periventricular nucleus (AVPV) to exert neuroendocrine control ...
Recombinant Goat VEGF164 Increases Hair Growth by Painting Process on the Skin of Shaved Mouse
Goat Vascular Endothelial Growth Factor (VEGF) Recombinant Protein Hair Growth
2016/5/17
To detect goat vascular endothelial growth factor (VEGF)-mediated regrowth of hair, full-length VEGF164 cDNA was cloned from Inner Mongolia cashmere goat (Capra hircus) into the pET-his prokaryotic ex...
Molecular Basis and Modification of a Neural Crest Deficit in a Down Syndrome Mouse Model
Down syndrome mouse models EGCG development Dyrk1a
2015/5/22
Down syndrome (DS) is the result of trisomy of human chromosome 21 (Hsa 21) and occurs in approximately 1/700 live births. Mouse models of DS have been crucial in understanding the gene-phenotype rela...
Effects of Trichostatin A on Cumulus Expansion during Mouse Oocyte Maturation
Mouse Cumulus-oocyte Complex Cumulus Expansion TSA
2016/5/12
This study was conducted to investigate the effects of Trichostatin A (TSA) on cumulus expansion during mouse oocyte maturation. TSA treatment inhibited cumulus expansion and significantly reduced the...
Isolation and Characterization of Parthenogenetic Embryonic Stem (pES) Cells Containing Genetic Background of the Kunming Mouse Strain
Mouse Parthenogenetical Activation Parthenogenetic Embryonic Stem (pES) Cells Kunming Mouse (Mus musculus Km) Genetic Background
2016/5/5
Parthenogenetic embryonic stem (pES) cells could provide a valuable model for research into genomic imprinting and X-linked diseases. In this study, pES cell lines were established from oocytes of hyb...
Effects of Daidzein on Testosterone Synthesis and Secretion in Cultured Mouse Leydig Cells
Daidzein Testosterone StAR P450scc 3b-HSD-1 Mouse Leydig Cells
2016/4/29
The objective of this work was to study the direct effects of daidzein on steroidogenesis in cultured mouse Leydig cells. Adult mouse Leydig cells were purified by Percoll gradient centrifugation, and...
Stage-specific Expression of Lanosterol 14-Demethylase in Mouse Oocytes in Relation to Fertilization and Embryo Development Competence
Mouse Oocyte Lanosterol 14 -Demethylase In vitro Fertilization Early Embryo Development
2016/4/29
Follicular fluid meiosis-activating sterol (FF-MAS) has been suggested as a positive factor which could improve the oocyte quality and subsequent embryo development after in vitro fertilization. Howev...
The Effect of Cryopreservation on the Mouse Embryos at Various-pronuclear Stages
Inner Cell Mass Mouse Pronuclear Embryo Slow Freezing Vitrification
2016/4/29
This study was carried out to establish an appropriate condition for the efficient cryopreservation of the mouse pronuclear embryo. In vitro cryopreservation of pronuclear embryos was carried out by s...
Recent Progress in Biotechnology-based Gene Manipulating Systems to Produce Knock-In/Out Mouse Models
Transgenic Knock In/Out ROSA26 Tetraploid ES Cells Gene Manipulation
2016/4/27
Gene-manipulated mice were discovered for the first time about a quarter century ago. Since then, numerous sophisticated technologies have been developed and applied to answer key questions about the ...