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Artificial Enzyme:Protein Designed Entirely From Scratch Functions In Cells As A Life-Sustaining Catalyst（图）
Artificial Enzyme Protein Designed Entirely Scratch Functions In Cells Life-Sustaining Catalyst
2018/2/1
A dawning field of research, artificial biology, is working toward creating a genuinely new organism. At Princeton, chemistryprofessor Michael Hecht and the researchers in his lab are d...
Old enzyme,new role
Old enzyme new role
2017/2/16
A team of researchers at the University of Delaware has discovered a new function for an enzyme that has long been known to have a central role in bacterial metabolism.Maciek Antoniewicz, Centennial J...
Dissecting Proton Delocalization in an Enzyme’s Hydrogen Bond Network with Unnatural Amino Acids
Dissecting Proton Delocalization Enzyme’s Hydrogen Bond Network Unnatural Amino Acids
2016/5/25
Extended hydrogen bond networks are a common structural motif of enzymes. A recent analysis proposed quantum delocalization of protons as a feature present in the hydrogen bond network spanning a tria...
Quantum delocalization of protons in the hydrogen-bond network of an enzyme active site
ab initio path integral molecular dynamics enzyme hydrogen bonding nuclear quantum effects proton delocalization
2016/5/25
Enzymes use protein architectures to create highly specialized structural motifs that can greatly enhance the rates of complex chemical transformations. Here, we use experiments, combined with ab init...
A Thermodynamic Framework For Identifying Free Energy Inventories of Enzyme Catalytic Cycles
Steroid Isomerases Catalysis Hydrogen-Ion Concentration Thermodynamics Models, Chemical
2016/5/25
Pauling's suggestion that enzymes are complementary in structure to the activated complexes of the reactions they catalyze has provided the conceptual basis to explain how enzymes obtain their fantast...
Quantitative,Directional Measurement of Electric Field Heterogeneity Within an Enzyme Active Site
Quantitative Directional Measurement Electric Field Heterogeneity Enzyme Active Site
2016/5/25
Extensive structural studies of enzymes have revealed that biological catalysis occurs within sequestered active site crevices, where reacting substrates are surrounded by an anisotropic and chemicall...
WEST LAFAYETTE, Ind. - Purdue researchers have discovered the structure of the enzyme that makes cellulose, a finding that could lead to easier ways of breaking down plant materials to make biofuels a...
汕头大学医学院七年制本硕临床医学生化与分子生物学课件Chapter3 enzyme。
Single-enzyme analysis in a droplet-based micro-and nanofluidic system
Single-enzyme analysis droplet micro nanofluidic system
2016/12/2
The kinetic activity of individual enzyme molecules was determined in aqueous droplets generated in a nano- and microfluidic device. To avoid high background noise, the enzyme and substrate solution w...