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For most people, the drip, drip, drip of a leaking faucet would be an annoyance. But for Georgia Institute of Technology Ph.D. candidate Alexandros Fragkopoulos, what happens inside droplets is the st...
Microbial protein targets: towards understanding and intervention
Microbial protein structure Biochemical analyses
2016/7/29
The symposium will bring together leading expertise in protein structure determination, biochemical characterisation and chemical biology to explore the most recent advances in the understanding
of p...
Understanding mitochondrial biogenesis through gene relocation
Yeast the genes oxidative phosphorylation enzymes proteins small ribosomes membrane protein the catalyst
2014/12/11
The yeast mitochondrial genome encodes seven hydrophobic subunits of oxidative phosphorylation enzymes and Var1p, an essential protein in the small ribosomal subunit. Expression of the membrane protei...
Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK
Hsp70 Protein aggregation Enzyme Polypeptide Protein function Nucleotides. The ATP hydrolysis
2014/12/11
The Hsp70 family molecular chaperones prevent protein aggregation under heat shock conditions. They are highly conserved, and have a N-terminal ATPase domain, which binds and hydrolyzes ATP, and a C-t...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Ribosomes the extension of cyclic code metastable state catalytic interactive translocation protein
2014/12/11
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pre-translocation state, the ribosome transitio...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Biological sciences Hybrid state L1 Ribosome rRNA Translocation
2014/12/10
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pretranslocation state, the ribosome transition...
An Integrative Approach Towards Understanding The Structure- Function Relationship Of The Epigenetic Regulator Methyl Cpg Binding Protein 2
Pure sciences Biological sciences Epigenetic regulator Methyl CpG Binding protein 2 Binding dynamics of caps Chromatin architectural proteins (caps) Intrinsically disordered protein Nucleosome Protein folding
2014/12/10
Methyl CpG binding protein 2 (MeCP2) is a methylated DNA binding protein which, when mutated, leads to a severe neurodevelopmental disorder known as Rett syndrome (RTT). In the present work I have sho...