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Period (Per1、Per2、Per3)基因广泛分布于生物体中,对许多生物的昼夜节律、细胞周期、DNA损伤修复起重要的作用。目前许多研究结果显示,Period基因是一种抑癌基因,与乳腺癌的发生密切相关,其启动子高甲基化导致了其在乳腺癌中表达下调。本文就Period基因与乳腺癌关系的研究进展进行综述。
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts
BMI adults genetics twins international comparisons
2018/11/15
Background: Genes and the environment contribute to variation in adult body mass index [BMI (in kg/m2)], but factors modifying these variance components are poorly understood.
Effects of thermal manipulation during late incubation period on post-hatch thermotolerance in ostrich
ostrich embryo heat stress hatchability blood biochemicals epigenetic
2016/11/11
The effects of thermal manipulation (TM) during late ostrich embryonic development on hatchability, body weight, biochemical and hormonal changes, and the ability of hatching chicks to cope with therm...
Factors in Dry Period Associated with Intramammary Infection and Subsequent Clinical Mastitis in Early Postpartum Cows
Dry Period Clinical Mastitis Intramammary Infection
2016/5/20
The objective of this study was to determine cow characteristics and farm management factors during the dry period associated with early postparturient intramammary infection (IMI) and subsequent clin...
Outcome of home parenteral nutrition in 251 children over a 14-y period: report of a single center
home parenteral nutrition children outcome complications growth
2018/11/30
Background: Parenteral nutrition (PN) is the main treatment for intestinal failure.
Objective: We aimed to review the indications for home parenteral nutrition (HPN) in children and describe the outc...
Soil management practice effect on water balance of a dryland soil during fallow period on the Loess Plateau of China
deep percolation fallow efficiency modelling
2016/2/22
To understand the mechanisms affecting water balance partitioning during fallow on drylands could improve the fallow management practices in arable land ecosystems. A three-year field experiment was c...
Study on the Changes in Enzyme and Insulin-like Growth Factor-1 Concentrations in Blood Serum and Growth Characteristics of Velvet Antler during the Antler Growth Period in Sika Deer (Cervus nippon)
Antler Blood enzyme IGF-1 Sika Deer
2016/5/18
This study was conducted to investigate changes in blood enzyme parameters and to evaluate the relationship between insulin-like growth factor-1 (IGF-1), antler growth and body weight during the antle...
Effect of Indigenous Herbs on Growth, Blood Metabolites and Carcass Characteristics in the Late Fattening Period of Hanwoo Steers
Herb Carcass Characteristic Blood Metabolite Hanwoo Steer
2016/5/12
This study was conducted to evaluate the effects of indigenous herbal supplements on growth, blood metabolites and carcass characteristics in the late fattening period of Hanwoo steers. In a 6 month f...
Influence of Ionophore Supplementation on Growth Performance, Dietary Energetics and Carcass Characteristics in Finishing Cattle during Period of Heat Stress
Monensin Lasalocid Feedlot Cattle Heat Stress Performance
2016/5/12
Forty-eight crossbred heifers (378.1±18 kg) were used in a 56-d feeding trial (four pens per treatment in a randomised complete block design) to evaluate the influence of ionophore supplementation on ...
Gene Expression Profiling in the Pituitary Gland of Laying Period and Ceased Period Huoyan Geese
Suppression Subtractive Hybridization Quantitative Real-time PCR
2016/5/12
Huoyan goose is a Chinese local breed famous for its higher laying performance, but the problems of variety degeneration have emerged recently, especially a decrease in the number of eggs laid. In ord...
Presence of Transcription Factor OCT4 Limits Interferon-tau Expression during the Pre-attachment Period in Sheep
Interferon-tau Transcription Gene regulation Implantation Sheep
2016/5/11
Interferon-tau (IFNT) is thought to be the conceptus protein that signals maternal recognition of pregnancy in ruminants. We and others have observed that OCT4 expression persists in the trophectoderm...
Infinite-Period Phase Transition versus Nucleation in a Stochastic Model of Collective Oscillations
Infinite-Period Phase Transition Collective Oscillations
2011/9/2
A lattice model of three-state stochastic phase-coupled oscillators has been shown by Wood et al. [Phys. Rev. Lett. 96, 145701 (2006)] to exhibit a phase transition at a critical value of the coupling...
Mammary Cell Turnover under High Temperature during the Dry Period in Dairy Cows
High Temperature Dry Period Cell Cycle Apoptosis Proliferation Dairy Cow
2016/5/6
The influence of high temperature on mammary cell turnover during the dry period is still unclear. The objective of this study was to investigate mammary cell turnover and p53 protein expression in th...
Effect of Ripening Period, Nitrite Level and Heat Treatment on the Chemical Characteristics of Turkish Dry Fermented Sausage (Sucuk)
Sucuk Dry Fermented Sausage Nitrite Heat Treatment Oxidation
2016/5/5
In order to determine the potential for reduction of nitrite levels and ripening period with heat treatment, the effects of ripening period (1-13 days), nitrite level (45-195 ppm), and heat treatment ...
ARTIFICIAL ADJUSTMENT OF FLOWER PERIOD AND HYBRIDIZING TECHNIQUES OF AMORPHOPHALUS KONJAC
Amorphophallus konjac artificial adjustment crossbreeding
2009/5/31
Under natural conditions, the four-to-five-year-old Plants of A. konjac bloom in April. By crossing with A. cor-rugatus, normal hybrid seeds were harvested. When konjac corms with flower buds were sto...