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Determination of the Carbon Monoxide Binding Constants of Myoglobin Mutants:Comparison of Kinetic and Equilibrium Methods
Binding Sites Carbon Monoxide Humans Kinetics Mutagenesis, Site-Directed Mutation Myoglobin Myoglobin Myoglobin Nitric Oxide Photolysis Protein Conformation Spectroscopy, Fourier Transform Infrared Structure-Activity Relationship
2016/5/23
The carbon monoxide (CO) binding constants of human myoglobin (Mb) and several single-site mutants have been determined using two different methods. In the kinetic method, which is commonly used for t...
Non-equilibrium Quantum Dynamics of Thermally Activated Transitions
Non-equilibrium Quantum Dynamics Thermally Activated Transitions
2011/1/6
We study the role of quantum fluctuations of atomic nuclei in thermally activated, out-of-equilibrium processes. To this goal we introduce an extension of the Dominant Reaction Pathways (DRP) formalis...
摘要
由于许多教科书中关于连锁平衡的介绍，多是引用结论或是推导不太严谨，使学生在学习群体遗传学时对理解连锁平衡的原理感到困难。本文从遗传平衡的基本条件出发，通过较严谨的数学推导，介绍了两个基因座的连锁平衡条件、平衡过程等原理，供教师和学生在群体遗传学教学中参考。Abstract: Because linkage equilibrium is introduced by directly quo...