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2024年5月14日，动物研究所科学数据中心林聪田博士与中国科学院城市环境研究所黄乾生研究员团队发挥各自数据优势，开展多学科数据交叉合作，共建“细胞外囊泡数据库”，相关数据论文成果以《EV-COMM: A database of interspecies and intercellular interactions mediated by extracellular vesicles》为题在细胞外...
苏州纳米所程国胜团队J Extracell Vesicles： Ang和TAT双肽修饰的工程化外泌体治疗脑胶质瘤的靶向递送策略（图）
程国胜 外泌体治疗 脑胶质瘤 靶向递送 生物毒性
2023/7/19
脑胶质瘤是指起源于脑神经胶质细胞的肿瘤，是最常见的原发性颅内肿瘤，我国脑胶质瘤年发病率为5~8/10万，五年病死率在全身肿瘤中仅次于胰腺癌和肺癌，这对人类生命健康产生巨大影响。目前，脑胶质瘤治疗以手术切除为主，但由于肿瘤的高侵袭性、快速生长和增强的血管生成，胶质瘤无法通过传统/常规手术进行干净切除，导致预后不良和生存时间短。针对有效抑制肿瘤生长和延长患者的生存期，化学药物疗法是结合手术切除治疗后最...
The 2016 Gordon Research Conference titled "Extracellular Vesicles" will present cutting edge research on the molecular, cellular and clinical translational aspects of the structure and function of ex...
the 1st Cold Spring Harbor Asia conference on Biology & Function of Extracellular Vesicles: Exosomes, Microvesicles & Beyond
Microvesicles Beyond
2016/7/29
We are pleased to announce the 1st Cold Spring Harbor Asia conference on Biology & Function of Extracellular Vesicles: Exosomes, Microvesicles & Beyond which will be held in Suzhou, China, located app...
Covalent Attachment of Lipid Vesicles to a Fluid-Supported Bilayer Allows Observation of DNA-Mediated Vesicle Interactions
Caspian and Black Sea waters reverse-osmotic desalination Na-zeolite softening of the permeate
2016/5/25
Specific membrane interactions such as lipid vesicle docking and fusion can be mediated by synthetic DNA-lipid conjugates as a model for the protein-driven processes that are ubiquitous in biological ...
Kinetics of DNA-mediated Docking Reactions Between Vesicles Tethered To Supported Lipid Bilayers
DNA electron transfer oxidative stress redox regulation
2016/5/25
Membrane-membrane recognition and binding are crucial in many biological processes. We report an approach to studying the dynamics of such reactions by using DNA-tethered vesicles as a general scaffol...
Diffusive Dynamics of Vesicles Tethered to a Fluid Supported Bilayer by Single-Particle Tracking
Calcium Macromolecular Substances 4-Chloro-7-nitrobenzofurazan DNA Lipid Bilayers Phosphatidylcholines Coated Materials, Biocompatible Nucleic Acid Hybridization Fluorescence Recovery After Photobleaching Diffusion
2016/5/24
We recently introduced a method to tether intact phospholipid vesicles onto a fluid supported lipid bilayer using DNA hybridization (Yoshina-Ishii, C.; Miller, G. P.; Kraft, M. L; Kool, E. T.; Boxer, ...
Arrays of Mobile Tethered Vesicles on Supported Lipid Bilayers
Oligonucleotides,Antisense Lipid Bilayers Phosphatidylcholines Fluorescent Dyes Liposomes
2016/5/24
We report a new system of laterally mobile, arrayed vesicles that are encoded with DNA to control tethering to fluid-supported phospholipid bilayers. The motion of individual fluorescently labeled ves...
Validation Of A Novel Vaccine Delivery System for Chlamydia Trachomatis Using Recombinant Gas Vesicles Derived From Halobacterium Salinarium
Biological sciences Health and environmental sciences Chlamydia Gas vesicles Halobacteria Std Vaccine Recombinant gas vesicles
2015/1/28
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted disease worldwide and while antibiotic treatment is effective in eliminating the pathogen, up to 70% of all infections are ...
Chinese Medicine Granule Affects the Absorption and Transport of Glucose in Porcine Small Intestinal Brush Border Membrane Vesicles under Heat Stress
Chinese Medicine Granule Heat Stress Pig Intestinal BBMVs Glucose Absorption
2016/4/29
This study was conducted to investigate the effects of Chinese medicine granule (CMG, including Cortex Phellodendron, Atractylodes Rhizome, Agastache Rugosa and Gypsum Fibrosum) on absorption and tran...