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Scientists Discover a Way to Sequence DNA of Rare Animals
Scientists Sequence DNA Rare Animals
2017/2/16
Rare and extinct animals are preserved in jars of alcohol in natural history museum collections around the world, which provide a wealth of information on the changing biodiversity of the planet. Thes...
Spatially localized generation of nucleotide sequence-specific DNA damage
sperm chemotaxis fertilization TPX-1 AEG CRISP
2016/5/23
Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate tha...
Haplogroup Classification of Korean Cattle Breeds Based on Sequence Variations of mtDNA Control Region
Haplogroup mtDNA Control Region Korean Cattle Breed Phylogenetic Tree
2016/5/20
Many studies have reported the frequency and distribution of haplogroups among various cattle breeds for verification of their origins and genetic diversity. In this study, 318 complete sequences of t...
Researchers Sequence Bedbug Genome,Find Unique Features
Researchers Sequence Bedbug Genome Unique Features
2016/2/23
The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increa...
Mitochondrial D-loop sequence variation among autochthonous horse breeds in Croatia
mtDNA genetic diversity horse
2015/6/8
Genetic variation in three Croatian coldblood horse populations was analysed using a sequence analysis of the proximal part (nt 15 498?5 821) of the D-loop region of mtDNA. Twenty unrelated horses wer...
Computational Mining and Survey of Simple Sequence Repeats (SSRs) in Expressed Sequence Tags (ESTs) of Dicotyledonous Plants
computational mining simple sequence repeats Expressed Sequence Tags
2015/5/26
DNA markers have revolutionized the field of genetics by increasing the pace of genetic analysis. Simple sequence repeats (SSRs) are repetitions of nucleotide motifs of 1 to 5 bases and are currently ...
Protein function prediction by integrating sequence, structure and binding affinity information
protein function binding affinity information
2015/5/26
Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to ...
Computational Mining and Survey of Simple Sequence Repeats (SSRs) in Expressed Sequence Tags (ESTs) of Dicotyledonous Plants
computational mining simple sequence repeats Expressed Sequence Tags
2015/1/9
DNA markers have revolutionized the field of genetics by increasing the pace of genetic analysis. Simple sequence repeats (SSRs) are repetitions of nucleotide motifs of 1 to 5 bases and are currently ...
Towards the isolation of esterase and amidase catalytic antibodies: Examination of germinal center diversity by cloning and sequence analysis of genes encoding monoclonal antibodies elicited by a transition state analogue
Esterase catalytic antibodies amidase amide ester hydrolysis reaction hybrid cells B cells the TSA induced antibodies genes cells cell lines
2014/12/11
In this study, a transition state analogue (TSA) approach was employed for the isolation of catalytic antibodies with esterase or amidase activity. The TSA used in this study, phosphonamidate, mimics ...
《Bioinformatics: Sequence and Genome Analysis》
Bioinformatics: Sequence and Genome Analysis
2014/7/17
书继承了冷泉港实验室出版物一贯的权威、经典的风格，全面系统地介绍了生物信息学的理论与应用。全书深入浅出、图文并茂、资料丰富、内容新颖，是从事和即将从事生物信息学研究的科研人员、技术人员、研究生的重要参考书和入门书。特色：1、专门为有生物学背景的读者精心设计；2、对内容的讲解极为清晰，并配有大量图示；3、用自然的语言讲解算法与理论，不是专家也能看懂；4、深入浅出，避免了大量使用复杂的公式与符号；5、...
CU-Boulder researchers sequence world's first butterfly bacteria, find surprises（图）
butterfly bacteria
2014/3/18
For the first time ever, a team led by the University of Colorado Boulder has sequenced the internal bacterial makeup of the three major life stages of a butterfly species, a project that showed some ...
Paradigm of Time-sequence Development of the Intestine of Suckling Piglets with Microarray
Intestinal Development Microarray Gene Expression Profile Network
2016/5/10
The interaction of the genes involved in intestinal development is the molecular basis of the regulatory mechanisms of intestinal development. The objective of this study was to identify the significa...
A Novel Sequence-Based Antigenic Distance Measure for H1N1, with Application to Vaccine Effectiveness and the Selection of Vaccine Strains
Influenza Vaccine effectiveness Antigenic distance pepitope Antigenic drift
2012/5/2
H1N1 influenza causes substantial seasonal illness and was the subtype of the 2009 influenza pandemic. Precise measures of antigenic distance between the vaccine and circulating virus strains help res...
Protein sequence and structure: Is one more fundamental than the other?
Protein sequence and structure Biomolecules Soft Condensed Matter
2012/4/28
We argue that protein native state structures reside in a novel "phase" of matter which confers on proteins their many amazing characteristics. This phase arises from the common features of all globul...
Chunking Patterns Reflect Effector-dependent Representation of Motor Sequence
Motor Sequence Chunking Patterns
2015/8/12
Sequential organization is central to much of human intelligent behavior ranging from everyday skills such as lacing shoes to using a computer. It is well known that such sequential skills involve cha...