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N-糖基化是蛋白质最普遍、复杂及重要的一种翻译后修饰之,位点特异的完整糖肽分析不仅能反映出特定糖型变化,并且可以指向特定的肽段及蛋白,近年来日益受到关注。然而,由于糖苷键和肽键碎裂能量不一致,各种质谱碎裂方式都只能获得部分定性信息,如高能碰撞裂解模式(Higher energy dissociation,HCD)下糖链产生糖和b/y型肽段片段,但可能导致在碎裂过程中失去全部或部分糖链修饰,而电子转...
National Science Review在线发表了中国科学院分子细胞科学卓越创新中心研究员季红斌研究组和中科院数学与系统科学研究院研究员王勇研究组合作的题为Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis的研究论文...
内质网自噬降解(ER-phagy)是近年来发现的一种选择性自噬途径,在细胞器更新和蛋白质降解中起着重要作用。其中,内质网到溶酶体的降解(ER-to-lysosome-associated degradation , ERLAD) 为蛋白质质量控制提供了一种不依赖蛋白酶体降解途径,对内质网更新和细胞内稳态至关重要,但它的作用过程和生物学功能尚未完全解明。目前用于研究这一过程的工具非常有限,其特异性的...
Scientists at the U.S National Science Foundation National Solar Observatory have predicted the emergence of a new sunspot group just in time for Thanksgiving.Using a technique called h...
2019年12月24日,《国家科学评论》(National Science Review)杂志以“A Global-scale multidecadal variability driven by Atlantic Multidecadal oscillation”为题,刊登了我院韩籍校聘教授杨咏岷(Young-Min Yang)的最新科学研究。
2020年6月8日,生物地质与环境地质国家重点实验室李超教授团队在白云石地质成因领域取得重要进展,相关成果发表于国际著名综合性学术期刊《PANS》,题目为《埃迪卡拉纪海洋大规模早期成岩白云石的形成:对“白云石之谜”的约束》,该实验室博士生常标为第一作者,生物地质与环境地质国家重点实验室李超教授、地质过程与矿产资源国家重点实验室黄俊华教授为共同通讯作者。
中国科学院大连化学物理研究所黄延强研究员和张涛院士在肼分解制氢方面的工作受到了国际同行的广泛关注,近期受邀在《国家科学评论》(National Science Review)上发表题为“Design strategies of highly selective nickel catalysts for H2 production via hydrous hydrazine decompositio...
The research and compilation of new century version of the National Huge Atlas of the People's Republic of China is the special basic work project by Ministry of Science and Technology of the People's...
Accompanying China's rapid urbanization in recent decades, especially in the new millennium, the housing problem has become one of the most important issues. The estimation and analysis of housing vac...
Urban shanty towns are communities that has contiguous old and dilapidated houses with more than 2000 square meters built-up area or more than 50 households. This study makes attempts to extract shant...
As the headstream of the Yellow River, the Yangtze River and the Lantsang River, located in the hinterland of Qinghai-Tibet Plateau, Qinghai province is hugely significant for ecosystem as well as for...
In this paper, a novel framework for spatial data processing is proposed, which apply to National Geographic Conditions Monitoring project of China. It includes 4 layers: spatial data storage, spatial...
The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth’s surface and it is the brand-new...
Build on soft soil, close to sea level the Netherlands is at high risk for the effects of subsidence and deformation. Interferometric Synthetic Aperture Radar (InSAR) is successfully used to monitor t...
Market-based emission trading schemes (ETSs) are widely used in the developed world to reduce greenhouse gas (GHG) emissions which are perceived as the source of global climate change. China, as the l...

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