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The islet beta cell is unique in its ability to synthesize and secrete insulin for use in the body. A number of factors including proinflammatory cytokines, free fatty acids, and islet amyloid are kno...
Raloxifene is an FDA approved agent used to treat bone loss and decrease fracture risk. In clinical trials and animal studies, raloxifene reduces fracture risk and improves bone mechanical properties,...
2014年5月5日,生化与细胞所陈玲玲课题组在《细胞研究》(Cell Research)发表当期封面文章“Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus”。该工作获得长非编码RNA研究领域著名科学家美国哈佛大学John L. Ri...
Human traumatic spinal cord injuries (SCI) are primarily incomplete contusion or compression injuries at the cervical spinal level, causing immediate local tissue damage and a range of potential funct...
Latent cytomegalovirus (CMV) infection has been shown to alter the lymphocyte response to acute aerobic exercise, likely due to the corresponding increase in exercise-responsive memory CD8+ T cells. I...
Introduction: Satellite cells (SCs) are of key importance in skeletal muscle tissue growth, repair, and regeneration. A single bout of high-force eccentric exercise has been demonstrated to increase m...
越来越多的研究表明,细胞可以通过操控其信号分子的某个时间段的行为,也就是动态行为,发送并接受信息。近期来自哈佛医学院的研究人员以此为焦点,介绍了信号动态编码和解码信号信息的研究进程,并指出信号分子动态作用机制传递细胞信息,未来也许能用于疾病的治疗。这一综述发表于Cell杂志上。
2012年11月7日下午,第三届赛诺菲-Cell Research优秀论文奖颁奖仪式在浙江杭州举行,Cell Research主编裴钢院士、中科院上海生命科学研究院生物化学与细胞生物学研究所党委书记、常务副所长景乃禾研究员,赛诺菲公司代表张愚等参加仪式并共同为获奖者颁奖。美国约翰•霍普金斯大学医学院程临钊教授,美国威斯康星大学麦迪逊分校James A Thomson与加利福尼亚大学圣地...
目的分研究双氯芬酸对人巨噬细胞电压依赖性钾通道Kv1.3、内向整流钾通道Kir2.1表达的影响及意义。方法以健康人外周血单核细胞源性巨噬细胞对象,采用Real-time RT-PCR及Western blot技术研究双氯芬酸对Kv1.3和Kir2.1表达的影响;电压敏感染料膜电位标测技术分析膜电位的变化,并用酶荧光化学法检测摄取氧化修饰低密度脂蛋白(OxLDL)的巨噬细胞内胆固醇酯(CE)的构成比...
山东大学生医学院研究生侯勇在国际顶级生物学学术期刊《细胞》(Cell)上发表两篇论文,一篇为第一作者,一篇为共同作者,排名第二。文章分别为《Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm》、《Single-Cell Exome Sequencin...
University of Queensland scientists have developed a world-first method for producing adult stem cells that will substantially impact patients who have a range of serious diseases.
Background: While mesenchymal stem cells (MSCs) have been isolated from multiple tissue sources, the differences existed between the cells from different tissues have still remained to be clarified. T...
To determine whether red cell distribution width could be used for the assessment of disease activity in patients with inflammatory bowel disease. Materials and methods: A total of 165 patients with i...
Production of volatile sulphides in cell cultures of Allium porrum is described. Allium porrum calluses were initiated from whole seedlings. The high growth rate of Allium porrum callus was achived in...
Background: Hematopoietic stem cell (HSC) transplantation has brought the possibility of the use of high dose chemotherapy in the treatment of malignant hematopoietic diseases. Short-term HSC preserva...

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