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中国科学院动物研究所专利：MONOCLONAL ANTIBODY AGAINST HUMAN PRPC AND USE THEREOF
中国科学院动物研究所 专利 人PrPC蛋白 单克隆抗体
2024/5/31
一种抗人PrPC蛋白的单克隆抗体，能够以靶向方式降低转录因子Twist1的表达水平，并诱导巨噬细胞和NK细胞靶向直肠癌肿瘤细胞。 抗体与西妥昔单抗联合用药的抑瘤效果也优于单用抗体或西妥昔单抗。
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Development and Characterization of a Novel Anti-idiotypic Monoclonal Antibody to Growth Hormone, Which Can Mimic Physiological Functions of Growth Hormone in Primary Porcine Hepatocytes
Monoclonal Anti-idiotypic Antibodies (Mab2s) Porcine Hepatocytes
2016/5/18
B-32 is one of a panel of monoclonal anti-idiotypic antibodies to growth hormone (GH) that we developed. To characterize and identify its potential role as a novel growth hormone receptor (GHR) agonis...
Validation of a monoclonal antibody-based ELISA for the quantification of the furazolidone metabolite (AOZ) in eggs using various sample preparation
monoclonal ELISA nitrofuran AOZ eggs sample preparation validation
2015/3/5
A monoclonal-based ELISA, coupled with an assay buffer, solvent and solid phase extraction procedures, was validated for use in the monitoring of egg samples for 3-amino-2-oxazolidinone (AOZ). The pro...
Sensitivity and specificity of monoclonal antibody Mn-Cs1 for detection and determination of Clavibacter michiganensis subsp. sepedonicus, the causal agent of bacterial ring rot of potato
bacterial ring rot of potato Clavibacter michiganensis subsp sepedonicus DAS-ELISA
2015/1/28
Monoclonal antibody Mn-Cs1 with a high level of sensitivity and specificity for detection and determination of Clavibacter michiganensis subsp. sepedonicus was prepared. Strain C. m. subsp. sepedonicu...
Monoclonal antibody treatment to prolong the secondary cardiac allograft survival in alloantigen-primed mice
Monoclonal antibody mice
2013/6/26
We have previously shown that costimulation blockade using a combination of monoclonal antibodies (mAbs) - CTLA4Ig, antibodies to CD154, LFA-1, and OX40L - can induce tolerance of cardiac allografts i...
Evaluation of tumor targeting with radiolabeled F(ab)2 fragment of a humanized monoclonal antibody
Humanized monoclonal antibody F(ab)2 fragment I-125
2010/1/6
Humanized monoclonal antibody U36 and its F(ab')2 fragment, radio labeled with 125I, were tested for tumor localization in nude mice bearing a squamous cell carcinoma xenograft line derived from a hea...
Autosomal Recessive Chronic Granulomatous Disease,IgA Deficiency and Refractory Autoimmune Thrombocytopenia Responding to Anti-CD20 Monoclonal Antibody
Anti-CD20 Autoimmune thrombocytopenia Chronic granulomatous disease IgA deficiency Primary immunodeficiency diseases
2009/12/17
Immunodeficiency and autoimmune disease may occur concomitantly in the same individual. Some of the immunodeficiency syndromes, especially humoral defects are associated with autoimmune disorders. Hem...
《Current Trends in Monoclonal Antibody Development and Manufacturing》（图）
Current Trends in Monoclonal Antibody Development and Manufacturing Steven J. Shire Wayne Gombotz Karoline Bechtold-Peters James Andya
2013/12/4
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years...
Preparation of Monoclonal Antibody Against Chicken Apolipoprotein B and Development of Enzyme Liked Immunosolvent Assay (ELISA) Method with the Antibody Aiming at the Optimization of Lipid Metabolism in Chickens
apolipoprotein B monoclonal antibody enzyme linked immunosorbent assay fat deposition broiler chickens
2009/7/31
Apolipoprotein B (apoB) containing lipoproteins are major lipoproteins in blood and the elevated concentration in plasma may lead to increased transport of lipoproteins into adipose tissues resulting ...
Production of Monoclonal Antibody Specific for Human Hemoglobin
Institue for Genetic Engineering and Biotechnology,TÜ Bİ TAK Marmara Research Center,Gebze,Kocaeli Department of Medical Biology,Faculty of Medicine,Marmara University,İ stanbul-TURKEY
2009/6/29
Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually impli...
Measurement of Urine Albumin Levels With A Monoclonal Antibody Based in-House Elisa
Human albumin Monoclonal antibody Polyclonal antibody ELISA
2009/6/25
Microalbuminuria is considered to be an early indicator of diabetic nephropathy. We have previously reported the establishment of A-HAlb/98 hybridoma secreting monoclonal antibody that specifically re...
Molecular characterizations of an intraacrosomal antigen defined by HS-33 monoclonal antibody
Sperm antigen anti-sperm antibodies acrosome reaction
2009/2/17
Among the numerous anti-sperm monoclonal antibodies generated in our laboratory, HS-33 was shown to react with a conserved antigen on the acrosome of spermatozoa from human and mouse. By using ind...
Stage-specific expression of a protein of the acrosome of baboon sperm during spermiogenesis detected with a monoclonal antibody
Spermatogenesis spermiogenesis acrosome monoclonal antibody
2009/2/7
A single monoclonal antibody, BSA4, raised against baboon epididymal sperm was used to study the ontogeny of the baboon sperm acrosome region during testicular spermiogenesis. This antibody is not s...
Monoclonal Antibody From Vasectomized Mouse Identifies a Conserved Testis-Specific Antigen TSA70
Vasectomy testicular auto antigen acrosomal matrix capacitation
2008/12/23
Vasectomy results in the occlusion of testicular outflow, leading to autoimmunity characterized by the production of antisperm antibodies (ASA). Reports on the rise in ASA following vasectomy in sev...