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Inspired by sutures developed thousands of years ago, MIT engineers have designed “smart” sutures that can not only hold tissue in place, but also detect inflammation and release drugs.
One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can accou...
A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and ...
痛风是一种以嘌呤代谢障碍,高尿酸血症为基础,导致关节和肾脏等全身多系统受累的炎症性免疫疾病。痛风性关节炎的特征是单钠尿酸盐结晶在关节内和关节周围沉积,急性发作时可引起关节局部红、肿、热、痛,影响全世界约6~10亿人。随着物质生活水平的提高,我国截至目前高尿酸血症患者约有1.4亿人,痛风患者超过1000万人。痛风除了影响关节以外,也与慢性肾病、心血管疾病、脑血管疾病和性功能障碍发生有关。痛风治疗的关...
Pharmaceutical companies are using artificial intelligence to streamline the process of discovering new medicines. Machine-learning models can propose new molecules that have specific properties which...
Stimulating the body’s immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies to achieve that: taking off the brakes that tumors put ...
When Sharif Tabebordbar was a teenager, his father began having trouble walking. Soon, he became wheelchair-bound and was diagnosed with a rare genetic muscle disease.
In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune dis...
Bacterial infections relating to medical implants place a huge burden on healthcare and cause great suffering to patients worldwide. Now, researchers have developed a new method to prevent such infect...
Researchers at Oregon State University have taken a key step toward new drugs and vaccines for combating COVID-19 with a detailed biophysical study of one protein's interactions with the SARS-CoV-2 ge...
When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time. When the drug disso...
Plant-derived chemicals called cardenolides have long been used to treat heart disease and have shown potential as cancer therapies. But the compounds are toxic, making it difficult for doctors to pre...
Scientists have developed a probe named CoxFluor that can distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and the enzyme Cyclooxygenase-1,...
A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff -- a virulen...
Objective. To examine if personalized learning objectives influenced student engagement and if achievement of objectives could be measured from course assignments. Methods. Learners created personali...

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