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近日，国际疼痛研究协会（IASP）官方杂志PAIN以封面故事正式发表（2022年4月6日Online Ahead）基础医学院王德恒副研究员和中西医结合研究院柯尊记教授联合团队的最新研究成果Altered pain sensitivity in 5×familial Alzheimer disease mice is associated with dendritic spine loss in a...
2021年4月30日，湘雅医院麻醉科朱小燕博士在美国辛辛那提大学留学期间完成的科研论文《Sympathectomy decreases pain behaviors and nerve regeneration by downregulating monocyte chemokine CCL2 in dorsal root ganglia in the rat tibial nerve crush...
针刺频次相关临床试验首次发表于疼痛领域顶级期刊——PAIN（图）
针刺频次 临床试验 膝骨关节炎
2023/6/25
针刺频次是针刺治疗方案的重要内容，也是影响针刺疗效的关键因素，但在临床实践中，针刺频次的选择缺乏必要的科学依据。在国内，针刺频次多为每周3-5次，但在国外，针刺频次多为每周1-2次。针刺频次过低不利于针刺疗效的发挥；针刺频次过高，可能出现针刺耐受，且治疗花费和时间成本高，不利于针刺疗法在世界范围推广，亦不符合成本效益原则。因此，有必要探讨不同针刺频次的应用规律。2020年10月21日，国际疼痛研究...
通过克隆十字花科蔬菜重要害虫菜青虫Pieris rapae瞬时感受器电位通道中的Painless（Pain）基因，实现它的体外功能性表达，为进一步研究其在鳞翅目昆虫中的生理功能提供重要依据。根据菜青虫的转录组数据，采用RT-PCR克隆菜青虫Pain基因得到完整开放阅读框；利用哺乳动物表达系统在体外表达菜青虫Pain离子通道。鉴定出菜青虫Pain基因是GenBank登录号为NW_019093434....
2017年10月28日，国际麻醉学和疼痛学权威学术期刊，国际疼痛研究联合会官方杂志《Pain》 （中科院JCR分区：医学1区，麻醉学1区）在线发表江苏省麻醉学重点实验室（江苏省麻醉学国家重点实验室培育建设点／江苏省麻醉与镇痛应用技术重点实验室）曹君利课题组的研究论文，该研究阐明了中脑多巴胺奖赏系统在调控疼痛和抑郁样行为中具有环路特异性的特征。这是该课题组继在 “Biological Psychia...
2017第一届心理健康与福祉，痛苦与痛苦工具与算法研讨会（1st Workshop on Tools and Algorithms for Mental Health and Wellbeing, Pain, and Distress）
2017 第一届 心理健康与福祉，痛苦与痛苦工具与算法 研讨会
2017/9/25
Distress - e.g. pain, panic, confusion, itching - in patients with restricted communicative verbal abilities such as neonates and children, somnolent patients and patients with dementia is difficult t...
Early-Life Pain May Lead To Obesity Risk,Especially In Females,Neuroscience Institute Study Finds
Early-Life Pain Obesity Risk Females Neuroscience Institute
2017/7/24
Inflammatory pain at birth changes how the hippocampus, a part of the brain associated with memory and eating behavior, works later in life, and this pain also causes adult rats to eat more frequently...
Chronic Pain Amplifies the Brain’s Reaction to New Injuries
Chronic Pain Amplifies Brain’s Reaction New Injuries
2017/7/20
Chronic pain in any one body part may distort the intensity with which a key brain region perceives pain everywhere else.This is the finding of a study in rats, which was led by researchers at NYU Lan...
Triathletes Lose Their Advantageous Pain Modulation under Acute Psychosocial Stress
ATHLETES PAIN PERCEPTION PAIN MODULATION CORTISOL STRESS REACTIVITY
2018/4/24
Introduction Triathletes, who constantly engage in intensely stressful sport, were recently found to exhibit greater pain tolerance and more efficient pain inhibition capabilities than nonathletes. Ho...
Hallucinating Pain
Hallucinating Pain
2016/6/15
The standard interpretation of quantum mechanics and a standard interpretation of the awareness of pain have a common feature: Both postulate the existence of an irresolvable duality. Whereas many phy...
Scientists Discover and Test New Class of Pain Relievers
Scientists Test New Class Pain Relievers
2016/6/12
A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain.These proof-of-concept exper...
Muscle Pain as a Regulator of Cycling Intensity: Effect of Caffeine Ingestion
EXERCISE PERRORMANCE ADENOSINE ANTAGONISM
2017/4/13
Caffeine ingestion improves endurance time trial performance. However, the ergogenic mechanism of action remains unresolved. One potential explanation for caffeine’s performance-enhancing effect is an...
Externalizing the Private Experience of Pain: A Role for Co-Speech Gestures in Pain Communication?
Pain Externalizing
2015/12/21
Despite the importance of effective pain communication, talking about pain represents a major
challenge for patients and clinicians because pain is a private and subjective experience.
Focusing prim...
Decreased Activity in Neuropathic Pain Form and Gene Expression of Cyclin-Dependent Kinase5 and Glycogen Synthase Kinase-3 Beta in Soleus Muscle of Wistar Male Rats
Neuropathic Pain Soleus Muscle CDK5 Protein Kinase
2015/11/6
Background: The relationship between decreased activity/neuropathic pain and gene expression alterations in soleus muscle has remained elusive.
Unscheduled Return Visits and Leaving the Chest Pain Unit Against Medical Advice
Chest Pain Against Medical Advice Return Visits
2015/11/6
Background: Rate of Unscheduled Return Visits (URVs) to the Emergency Department has been considered as a key indicator for evaluating the quality of the Emergency Department care for decades. A highe...