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Classify hyperdiploidy status of multiple myeloma patients using gene expression profiles
Classify hyperdiploidy status multiple myeloma patients expression profiles
2016/1/25
Multiple myeloma (MM) is a cancer of antibody-making plasma cells. It frequently harbors alterations in DNA and chromosome copy numbers, and can be divided into two major subtypes, hyperdiploid (HMM) ...
The shaping and functional consequences of the dosage effect landscape in multiple myeloma
shaping functional consequences dosage effect landscape multiple myeloma
2016/1/25
In this paper we study the conditional limit theorems for critical continuous-state branching processes with branching mechanism ψ(λ) = λ 1+α L(1/λ)where α ∈ [0,1] and L is slowly varying at ∞. We pro...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/25
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Classify hyperdiploidy status of multiple myeloma patients using gene expression profiles
Classify hyperdiploidy status multiple myeloma patients expression profiles
2016/1/20
Multiple myeloma (MM) is a cancer of antibody-making plasma cells. It frequently harbors alterations in DNA and chromosome copy numbers, and can be divided into two major subtypes, hyperdiploid (HMM) ...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/20
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
New antimyeloma drugs in spinal cord infiltration for multiple myeloma. Determination of lenalidomide in cerebrospinal fluid with ultrasensitive high-performance liquid chromatography
Lenalidomide Multiple Myeloma Spinal Cord Infiltration
2013/1/30
A 64-year-old woman with IgA kappa multiple myeloma was treated with thalidomide-dexa- methasone. Due to progression of the disease, bortezomib, doxorubicin and dexamethasone were administered, follow...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Transformation of chronic myelogenous leukemia to Multiple Myeloma:A case report
Myeloid Chronic Cell transformation Neoplastic Philadelphia chromosome
2009/12/25
Chronic myelogenous leukemia (CML) is a stem cell disorder sometimes associated with lymphoproliferative disorders. CML may precede a lymphoproliferative disorder. There are a few reports showing asso...
The Effects of Arsenic Trioxide and Zoledronic Acid on Malignant Plasma Cells Derived from Bone Marrow Cells of Multiple Myeloma Patients
Multiple myeloma Arsenic trioxide Zoledronic acid Real time PCR Gene expression
2009/12/14
Background: Multiple myeloma (MM) is a disease of plasma cells that has fatal consequences. New agents associated with molecular targets have prompted clinical investigators to design new treatme...
Frequent macroscopic hematuria in multiple myeloma is quite rare and exceptional and no report has been found in the literature. We have presented a case of multiple myeloma who developed frequent epi...
Arterial Thrombosis in Refractory Multiple Myeloma Patient Treated with Thalidomide and Dexamethasone:A Case Report
Multiple myeloma thalidomide arterial thrombosis
2009/6/19
A 48-year-old man with relapsing multiple myeloma (MM) presented with serum monoclonal protein (IgG l) of 5.93 g/dl. He was initially treated with four cycles of VAD (vincristine, adriamycin and dexam...
Sterile Corneal Ulcer and Sjögren’s Syndrome Associated with Long-Term Interferon alpha-2b Treatment in a Case of Multiple Myeloma
corneal ulcer interferon alpha-2b dry eyes Sjö gren’s syndrome immunosuppressant
2009/4/20
A 71-year-old Chinese male was referred for severe dry eyes who suffered from multiple corneal melting ulcers and underwent a long-term and high-dosage interferon alpha-2b (INFα-2b) treatment for mult...
Prognostic implications of p21（Waf1/Cip1）immunolocalization in multiple myeloma
Prognostic implications p21（Waf1/Cip1）immunolocalization multiple myeloma
2009/3/2
Protein p21 (Waf1/Cip1) plays a critical role in controlling the cell cycle especially as a check point of G1 and is intimately associated with important cellular activities including differentiatio...
Arsenic Trioxide Compound Modulates Multiple Myeloma Phenotypes: Assessment on Cell Line Models
Multiple myeloma Karpas 707 MMP-2 Angiogenesis Apoptosis Cytotoxicity Arsenic trioxide
2010/2/3
Recent evidences suggest that multiple myeloma phenotypes (MMPs) are involved in the infiltration of multiple myeloma-affected marrow foci. In this study, the effects of arsenic trioxide on the invasi...