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Synergistic Effect of Dexamethasone and Prolactin on VEGF Expression in Bovine Mammary Epithelial Cells via p44/p42 MAP Kinase
p44/p42 MAP Kinase Prolactin Dexamethasone VEGF Bovine Mammary Epithelial Cells
2016/4/29
Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis under various physiological and pathological conditions. We found that the VEGF isoforms VEGF120, VEGF164, and VEGF188 were...
妊娠合并糖尿病诱发胚胎先天性神经管缺陷动物模型的MAP 激酶信号传导机制MAP Kinase Signal Pathway in Hyperglycemia-induced Congenital Neural tube defects
神经管缺陷 糖尿病 激酶 ERK JNK/SAPK RAF-1 动物模型
2008/1/20
摘要
为了揭示妊娠合并糖尿病诱发胚胎先天性神经管缺陷的分子机制，并探讨其有效的防治方法。 实验选用6个实验组的 Sprague-Dawley 大鼠：第1组为常规饲养的正常对照组；第2组尾静脉注射65mg/kg Streptozotocin (STZ) 构建妊娠合并糖尿病、且诱发先天性神经管缺陷的实验组大鼠；第3组为STZ构建的糖尿病、但胚胎不伴有先天性神经管缺陷的大鼠模型；第4、5、6 组为 S...
期刊信息
篇名
Reduced expression of MAD2, BCL2, and MAP kinase activity in pig oocytes after in vitro aging are associated with defects in sister chromatid segregation during meiosis II and embryo fragmenta...
MAP Kinase is Activated dring the Maturation of Porcine Oocytes
Porcine Oocytes Maturation Western Blotting MAP Kinase Phosphorylation
2016/4/15
In an attempt to evaluate the function of MAP kinase in porcine oocytes and to develop a method of the assessment of its activity, myelin basic protein (MBP) was used as a substrate to detect the MAP ...