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Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants
Aluminum hydroxyphosphate Vaccine adjuvants Staphylococcus aureus
2023/6/21
Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants。
2 very different microbes immune to the same viruses? Scientists were puzzled.（图）
微生物 病毒免疫 深海细菌 古细菌 基因组分析
2023/6/19
In a study published in Nature Microbiology, Harvard researchers found evidence that viruses infecting microbes in the deep sea interact with a far more diverse set of hosts than previously thought. T...
Nanoparticles provoke immune response against tumors but avoid side effects（图）
纳米颗粒 肿瘤 免疫反应
2023/6/6
Cancer drugs that stimulate the body’s immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delive...
The immune system does battle in the intestines to keep bacteria in check（图）
Research Infectious Diseases Veterinary Medicine
2023/6/29
Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis. A relative, Yersinia pseudotuberculosis, causes gastrointestinal illness...
It’s been known for decades that astronauts’ immune systems become suppressed in space, leaving them vulnerable to disease, but the exact mechanisms of immune dysfunction have remained a mystery – now...
Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer...
Cornell researchers have for the first time successfully imaged the entire depth of the lymph nodes in a living mouse using three-photon microscopy. The breakthrough technique’s micrometer clarity and...
Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy（图）
递送 免疫系统 刺激药物 癌症免疫治疗
2023/6/7
Stimulating the body’s immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies to achieve that: taking off the brakes that tumors put ...
Immunotherapy is a promising strategy to treat cancer by stimulating the body’s own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovere...
cGAS-like receptors put a sting into the evolution of immune defence（图）
cGAS immune defence DNA 3'2'-cGAMP cGLR1 cGLR2
2021/8/10
Aspects of how immune defence processes evolved remain mysterious. Studies of the fly Drosophila melanogaster reveal previously unknown details of a defence pathway with echoes of, but key differences...
One reason it's so difficult to produce effective vaccines against some viruses, including influenza and HIV, is that these viruses mutate very rapidly. Mutation allows them to evade the antibodies ge...
Immune and circulatory systems are integrated in insects（图）
Immun circulatory systems integrated insects
2020/12/18
Biologists have found solid proof that among the insect tree of life, the relationship between the immune and circulatory systems is consistent. The discovery will help researchers understand how inse...
Wound-healing biomaterials activate immune system for stronger skin（图）
Wound-healing biomaterials activate immune system stronger skin
2020/11/20
Researchers at Duke University and the University of California, Los Angeles have developed a biomaterial that significantly reduces scar formation after wounding, leading to more effective ...
Scientists show jet lag impairs immune response in mice（图）
jet lag impairs immune response mice
2020/10/23
Imagine you've just arrived in Paris. Your body thinks it should be midnight -- a restorative time when your cells typically proofread DNA, organize and store energy, and perform other essential chore...
The D-lemma: narrow-band UV type B radiation versus vitamin D supplementation versus sunlight for cardiovascular and immune health
narrow-band UV type B vitamin D immune health
2018/11/13
In this issue of the Journal, Ponda et al. (1) report on the role of vitamin D and narrow-band UV type B (UVB) irradiation on the blood lipid profile of healthy adults. They previously observed that t...