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Recovery of 1-Chloro-2,4-dinitrobenzene Detoxification by N-acetyl- L-cysteine in Glutathione Predepleted Human Erythrocytes
GSH NAC Erythrocytes Xenobiotics Detoxification Free-SH
2009/6/23
Glutathione is an important thiol-containing compound involved in the detoxification process in erythrocytes. Its thiol group reacts with a variety of xenobiotics in a glutathione S-transferase cataly...
Acute effects and long-term sequelae of 1,3-dinitrobenzene on male reproduction in the rat. II. Quantitative and qualitative histopathology of the testis
1,3-dinitrobenzene male reproduction rat
2009/2/23
This study determined the quantitative and qualitative histopathologic effects of a single oral dose of 1,3-dinitrobenzene (48 mg/kg) on the rat testis from 1 to 175 days postexposure. The testis was ...
Acute effects and long-term sequelae of 1,3-dinitrobenzene on male reproduction in the rat. I. Sperm quality, quantity, and fertilizing ability
long-term sequelae 1,3-dinitrobenzene male reproduction rat
2009/2/23
Groups of eight adult male rats were given a single oral dose of 0 or 48 mg/kg of 1,3-dinitrobenzene and sacrificed at 1, 2, 4, 8, 16, 24, 32, 72, and 175 days posttreatment. The groups killed at 17...