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Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM Tension Nanoscale Ultrastructure Modulus
2014/11/6
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Impact of obesity and diabetes on arthritis: An update
Obesity Diabetes Arthritis Complications
2013/1/29
The incidence of obesity and diabetes has been increased with alarming rate in recent years and became a common problem around the globe including developing as well as in developed countries with inc...
Tubulointerstitial Nephritis Complicated with Primary Sjögren’s Syndrome under Treatment for Type 2 Diabetes Mellitus
Tubulointerstitial Nephritis Sjö gren’s Syndrome Type 2 Diabetes Mellitus
2013/1/31
Tubulointerstitial nephritis complicated by primary Sjögren’s syndrome in a patient under treatment for type 2 diabetes mellitus was diagnosed in the early stage of the disease by renal biopsy. T...
Long Term Results of Valve Operations in Patients with Diabetes
Cardiac Heart Valve Diabetes
2013/2/20
Diabetes Mellitus (DM) adversely affects survival in patients with Coronary Artery Disease (CAD) undergoing Coronary Artery Bypass Grafting (CABG) surgery. The influence of diabetes on events after va...
Urinary type IV collagen excretion predicts an increased urinary albumin-to-creatinine ratio in normoalbuminuric patients with diabetes
Type IV Collagen Diabetic Nephropathy Oxidative Stress Monocyte Chemoattractant Protein-1
2013/1/30
Aims: We evaluated whether urinary excretion of type IV collagen (U-COL) may predict an increase in the urinary albumin-to-creatinine ratio (ACR) and what factors regulate U-COL in 145 normoalbuminuri...
Cold agglutinin disease associated with mycoplasma infection in an individual with type 2 diabetes: An atypical case
Cold Agglutinin Disease Diabetes Mellitus Mycoplasma
2013/1/30
Cold Agglutinin Disease is a hemolytic anemia associated with cold reactive autoantibodies. Although the acute form of cold agglutinin disease can be attributed to autoimmune or infectious diseases an...
Comparison of the fatty acid composition of the serum phospholipids of controls, prediabetics and adults with type 2 diabetes
Pre-Diabetes Type 2 Diabetes Fatty Acids Phospholipids Fluidity
2013/1/30
Objective: Although abnormalities in the fatty acid composition of serum and red cell membrane phospholipids of patients with type 2 diabetes are well-documented, lacking are studies of this issue in ...
Atrial fibrillation in diabetes: A cause for concern?
Diabetes Atrial Fibrillation Mechanisms Treatment
2013/1/30
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and is associated with significant morbidity and mortality. It is becoming increasingly evident diabetes is a significant risk fa...
Visfatin levels are low in subjects with type 2 diabetes compared to age-matched controls
Visfatin Adiponectin Resistin Diabetes Insulin Resistance
2013/1/30
Background: Visceral adiposity correlates strongly with insulin resistance and components of metabolic syndrome. Visfatin is preferentially produced by human visceral adipose tissue. Objective: The ob...
Diabetes mortality and environmental heavy metals in North Carolina counties: An ecological study
Diabetes Mellitus Heavy Metals Air Pollution North Carolina
2013/1/30
Introduction: Arsenic, beryllium, cadmium and nickel have been associated with the prevalence of diabetes mellitus in populations exposed to these elements. However, diabetes mortality has not been ev...
Enzyme may hold the key to treating kidney disease and diabetes（图）
Enzyme kidney disease and diabetes
2009/12/17
Over £320,000 has been jointly awarded to Nottingham Trent University and The University of Sheffield by The Wellcome Trust, to fund important research into an enzyme which is believed to hold t...
A Common Polymorphism of Upstream Transcription Factor 1 Gene is associated with Lipid Profile: A Study in Chinese Type 2 Diabetes Families
dyslipidemia genetic epidemiology single nucleotide polymorphism type 2 diabetes mellitus upstream transcription factor
2009/10/30
Upstream transcription factor 1 (USF1) is capable of controlling various members in glucose and lipid metabolism pathways. Much evidence suggests that the rs3737787 polymorphism in the USF1 gene may l...
Bioinformatic Analysis of Functional Proteins Involved in Obesity Associated with Diabetes
bioinformatics resistin obesity and type two diabetes
2009/4/29
The twin epidemic of diabetes and obesity pose daunting challenges worldwide. The dramatic rise in obesity-associated diabetes resulted in an alarming increase in the incidence and prevalence of obesi...
Role of Raf-1 kinase in Diabetes-induced Accelerated Apoptosis of Retinal Capillary Cells
apoptosis diabetic retinopathy endothelial cells Raf-1 small molecular weight G-protein
2009/4/29
Small molecular weight G-proteins serve as fundamental signaling switches that regulate cell fates by coupling receptor activation to downstream effector pathways. H-Ras, a small molecular weight G-pr...
Identification of Biomarkers for Type 2 Diabetes and Its Complications: A Bioinformatic Approach
Type 2 diabetes biomarkers neuropathy nephropathy insulin resistance bioinformatics
2009/4/20
The long asymptomatic period before the onset of chronic diseases presents opportunities for disease prevention. Many chronic diseases like type 2 diabetes and its complications may be preventable by ...