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Effect of Shear Stress on RhoA Activities and Cytoskeletal Organization in Chondrocytes
Biomedical Engineering
2015/1/12
Mechanical force environment is a major factor that influences cellular homeostasis and remodeling. The prevailing wisdom in this field demonstrated that a threshold of mechanical forces or deformatio...
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
ECM (extracellular matrix) Hydrogel Mechanical properties Polyethylene oxide Smooth muscle cell
2010/1/7
Studies using 2-D cultures have shown that the mechanical properties of the extracellular matrix (ECM) influence cell migration, spreading,
proliferation, and differentiation; however, cellular mecha...