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N2,H2,and N2O antagonism of high pressure neurological syndrome in mice.
Inability of helium to influence the occurrence of arrhythmias in cats,rats,and mice.
The effects of hydraulic compression on heart rate and respiratory frequency were studied in liquid-breathing, hypothermic (17-31 degrees C) mice. Increasing the hydrostatic pressure caused a bradycar...
The histopathology of dysbaric osteonecrosis and the influence of the number of exposures, compression rate, and obesity on the incidence and latency of the lesion were studied in 438 mice (2505 bones...
Direct measurement of helium elimination in mice.
Swiss albino mice were exposed to normoxic (PO2 approximately 0.2 ATA) helium at 1, 20 or 35 ATA for 2 or 48 h and examined for the presence of bacteria and endotoxin in selected tissues. Among mice e...
The adrenocortical endocrine subsystem has been demonstrated to enhance mammalian tolerance to harsh environmental conditions, including hypoxia and temperature extremes. In a series of factorial expe...
Substances that stimulate smooth muscle have been previously implicated in the pathogenesis of decompression sickness. This concept was strongly supported by the demonstration that compounds that comb...
The ability of eight diverse pharmacological agents to ameliorate the high pressure nervous syndrome (HPNS) in mice was studied. Data were obtained for the end points: coarse tremors, complete spasms,...
The effect of change in injection pattern in nitrogen on threshold pressures of three symptoms associated with compression in helium/nitrogen atmospheres was explored. Excitement threshold pressures d...
Mice exposed to 50 ATA heliox pressure during one spermatogenic cycle subsequently exhibit subfertility which can recover over an 8-wk period. This study was designed to investigate the changes in spe...
The effect of hyperbaric oxygen (HBO) as an immunosuppressive agent was evaluated by using a highly immunogenic skin allograft mouse model. Immune-histoincompatible female C57BL/6 and BALB/c mice (N =...
The contents of oxygen free radicals (OFRs) and malondialdehyde (MDA) in S-180 sarcoma tissues were measured in four groups of mice: an untreated normoxic group, a normoxic hyperbaric group, a hyperba...
The mechanism by which 12 atm abs of a helium-oxygen gas mixture (heliox) antagonizes behavioral effects of ethanol is unknown. Although the threshold for pressure-reversal of general anesthesia and e...
Tumor cell kinetics were studied in C57 Bl/J mice with a transplantable sarcoma, MCG 101, exposed to hyperbaric oxygen (HBO2), 2.8 atm abs, 2 hours daily for 9 days or until spontaneous death. The iso...

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